KNOCK-IN Mouse Model 中文名: 基因敲入(KNOCK-IN)小鼠模型 中文别名: 基因敲入(KNOCK-IN)小鼠模型 CBNumber: CB05788341 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商4 基因敲入(KNOCK-IN)小鼠模型化学性质 安全信息 基因敲入(KNOCK-IN)小鼠模型性质、用途与生产工艺 ...
中文名称基因敲入(KNOCK-IN)小鼠模型 中文同义词基因敲入(KNOCK-IN)小鼠模型 英文名称KNOCK-IN Mouse Model 英文同义词KNOCK-IN Mouse Model CAS号 分子式 分子量0 EINECS号 相关类别 Mol文件Mol File 结构式 基因敲入(KNOCK-IN)小鼠模型 性质 基因敲入(KNOCK-IN)小鼠模型 用途与合成方法 ...
基因敲入(Knock-in)模型的应用: 模拟人类遗传机制,探索致病机制 示踪基因表达 进行谱系示踪,追溯细胞起源 将小鼠基因人源化,加速药物研发 将分子遗传学工具引入小鼠模型中 基因敲入模型包括: 常规基因敲入 点突变 条件性点突变 人源化 通过CRISPR基因编辑技术,构建一个基因敲入小鼠模型一般需要6-9个月。 通过...
Using data from thousands of knock-in mouse model projects completed by our team, we have collected new information demonstrating how our gene editing technologies push the boundaries of modifying large genomic regions.Below, we have outlined Cyagen’s large fragment knock-in (LFKI) capabilities acr...
In this study we used CRISPR/Cas9 to develop new "knock-in" models of CMTX1 that are more representative of the spectrum of mutations seen with CMTX1 than the Cx32 knockout (KO) mouse model used previously. We compared mice of four genotypes - wild-type, Cx32KO, p.T55I, and p.R7...
A tissue specific Knock-In mouse model developed by Creative Animodel, helps to insert new gene at a particular organ of the animal body using vector design and ES cell targeting technique.
Moreover, the development of these tissue lesions was highly sensitive to corticosteroid treatment like in IgG4-RD. For these reasons we consider the LatY136F knock-in mouse strain to represent a promising model for human IgG4-RD. 展开 关键词:...
Depressed Frank–Starling mechanism in the left ventricular muscle of the knock-in mouse model of dilated cardiomyopathy with troponin T deletion mutation ... Depressed Frank-Starling mechanism in the left ventricular muscle of the knock-in mouse model of dilated cardiomyopathy with troponin T ...
In addition, the hCD147KI-NSG mouse model allows further study of SARS-CoV-2 in the immunodeficiency condition which may assist our understanding of this virus in the context of high-risk populations in immunosuppressed states. Our data show (1) the human CD147 protein is expressed in ...
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