The host response to viral infection includes the induction of type I interferons and the subsequent upregulation of hundreds of interferon-stimulated genes. Ubiquitin-like protein ISG15 is an interferon-induced protein that has been implicated as a central player in the host antiviral response. Over...
5. S. Desai, M. Juncker , and C. Kim, "Regulation of mitophagy by the ubiquitin pathway in neurodegenerative diseases,"Exp Biol Med (Maywood), vol. 243, no. 6, pp. 554-562, 2018 6. Y. C. Perng , and D. J...
3. Shi C, et al. (2022) ZDHHC18 negatively regulates cGAS-mediated innate immunity through palmitoylation. Embo J 41(11):e109272. 4. Perng YC & Lenschow DJ (2018) ISG15 in antiviral immunity and beyond. Nat ...
4. Perng YC & Lenschow DJ (2018) ISG15 in antiviral immunity and beyond. Nat Rev Microbiol 16(7):423-439. 链接:
ISG15 in antiviral immunity and beyond 来自 Springer 喜欢 0 阅读量: 161 作者:YC Perng,DJ Lenschow 摘要: The host response to viral infection includes the induction of type I interferons and the subsequent upregulation of hundreds of interferon-stimulated genes. Ubiquitin-like protein ISG15 is ...
ISG15 in antiviral immunity and beyond. Nat Rev Microbiol. 2018;16(7):423–39. https://doi.org/10.1038/s41579-018-0020-5. Article CAS PubMed PubMed Central Google Scholar Zhao C, Collins MN, Hsiang TY, Krug RM. Interferon-induced ISG15 pathway: an ongoing virus-host battle. Trends...
Google Scholar Perng, Y.-C. & Lenschow, D. J. ISG15 in antiviral immunity and beyond.Nat. Rev. Microbiol.16, 423–439 (2018). Google Scholar Narasimhan, J. et al. Crystal structure of the interferon-induced ubiquitin-like protein ISG15....
J. ISG15 in antiviral immunity and beyond. Nat. Rev. Microbiol. 16, 423–439 (2018). Article CAS PubMed PubMed Central Google Scholar Hadjadj, J. et al. Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients. Science 369, 718–724 (2020). Article ...
2023, Nature Reviews Molecular Cell Biology Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection 2021, Nature Immunology ISG15 in antiviral immunity and beyond 2018, Nature Reviews Microbiology View all citing articles on Scopus 2 Lead Contact ...
Concordantly, humans with inherited ISG15 deficiency show impaired IFN-γ responses and fail to effectively counteract mycobacterial infection21. Beyond the function of ISG15 in immunity, ISGylation is involved in DNA repair22 and tumorigenesis23,24. Analogously to other post-translational control ...