isg15蛋白 结构ISG15蛋白是一种与免疫相关的蛋白质,全名为“干扰素诱导基因15”(interferon-stimulated gene 15)。其结构由两个部分组成:一个泛素样蛋白结构域(ubiquitin-like protein domain)和一个C末端尾巴(C-terminal tail)。泛素样蛋白结构域与其他蛋白质发生共价结合,起到调节蛋白质功能的作用。此外,ISG15蛋白...
Primary Antibody Dilution:1:1000 Cell Tissue Type:Human hippocampal progenitor cells FH Chaohui (Verified Customer) (10-19-2021) The antibody shows a high quality of free ISG15 and conjugated ISG15 spots Applications:Western Blot Primary Antibody Dilution:1:1000 ...
Cited in 65 publications. ISG15 antibody for WB, IHC, IF/ICC, IF-P, ELISA and reacts with human, mouse.
与Beclin-1具有潜在结合位点的miRNA,并分析其结合的自由能以及相关的物种保守性;采用干扰RNA和自噬抑制剂处理细胞,测定细胞胆固醇流出的影响.结果:ISG15可以增加THP-1巨噬细胞源性泡沫细胞胆固醇流出的能力.ISG15使LC3II/LC3I增加,并降低p62表达;miR-17-5p可以靶向作用Beclin-1,抑制Beclin-1的表达;ISG15通过抑制miR...
ISG15 induces an increase of IL-1β later during infection by leading to increased IL-1β producing CD8α+ dendritic cells at the site of infection. Here, we define for the first time the molecular determinants of active free ISG15 and link ISG15 to IL-1β production by CD8α+ ...
ISG15 抗体 | MedChemExpress (MCE) 英文名称: 总访问: 63 国产/进口: 进口 半年访问: 12 产地/品牌: MedChemExpress(MCE) 产品类别: 生化试剂 规格: 10 μL 最后更新: 2025-2-13 货号: HY-P80194 CAS 号: 参考报价: 470 立即询价 电话咨询 ...
摘要: 本发明涉及生物医药领域,特别是涉及RXR在筛选Ifnβ,Isg15,Gbp-1,Oas2,Irf7,Isg20,Ifn4激动剂中的用途。本发明发明人提供了RXR在筛选Ifnβ,Isg15,Gbp-1,Oas2,Irf7,Isg20,Ifn4激动剂中的用途以及RXR过度表达所引起的Ifnβ,Isg15,Gbp-1,Oas... 查看全部>> ...
1A, the mRNA expression of ISG15 in the PBMCs of T1D patients was almost three times greater than that in the PBMCs of controls. As shown in Discussion The pathogenesis of type 1 diabetes is unclear, and viral infections have been indicated to be important factors in its development. ...
The ISG15/USP18 pathway modulates cellular functions and is important for the host innate immune response to chronic viral infections such as Hepatitis C Virus (HCV). Interferon stimulated gene 15 (ISG15) was the first ubiquitin-like protein modifier identified. As in ubiquitination, ISG15 conjuga...