Which of the following two molecules is a stronger base: (CH_3)_4N+OH- or (CH_3)_3NH+OH-? Explain why so?Which of the following two molecules is a stronger base: (CH_3)_4N^+OH^- \text{ or } (CH_3)_3NH^+OH^-? ExplainWhich anion (A or B) is the stronger base?Which ...
Cyclohexylamine (C6H13N) reacts with benzoyl chloride (C7H5ClO) in a reaction with 1 M NaCO3 acting as the strong base. What is the major product and what is its name? Draw the SN1 mechanism for the reaction of (CH_3CH_2)_3C-Br with chloride ion. ...
In the absence of their acid/base residue, thioglycoligases require both an activated glycosyl donor to form the glycosyl-enzyme intermediate and an acceptor that is a strong nucleophile, capable of reacting without basic catalytic assistance (Fig. 1a); consequently, nucleophiles successfully assayed ...
In CGI-58, Asn155 replaces the putative active site nucleophile. A large, primarily helical lid region (Pro180–Leu280) is inserted after strand β6 and covers the potential “active site.” An additional feature of the model is a long partly helical, partly unstructured region ranging from...
Because every nucleophile is potentially a base, and vice versa. If you have a reaction where it looks like you might get SN2 or E2, look closely first – is there any chance of a simple acid-base reaction? For instance, take NaOH plus an alkyl thiol, R–SH. Is it an SN2? Or ...
Here we bring extensive bioinformatics, in vivo and in vitro experimentation to compose a unified view of the biosynthesis of these widely distributed non-canonical amino acids that both derive by pyridoxal-mediated β-elimination of the activated O-phosphorylated substrates followed by β-addition of...
The process of the -invention may be carried out, for example in the presence of a suitable dehydrating agent (such as: a strong acid (e.g. sulfuric acid (e.g. concentrated sulfuric acid), methanesulfonic acid (e.g. anhydrous methanesulfonic acid) and the like); an acid anhydride such ...
Which of the following is considered a strong base? a. NH3 b. Be(OH)2 c. Mg(OH)2 d. Ba(OH)2 Consider these three anions. 1. Which one is the strongest base? 2. Which one the weakest base? 3. Which one is the nucleophile? What is the stronger base, OH^- or ...