This is a 28-nucleotide 5′-UTR sequence in the ferritin mRNA , it is necessary for iron regulation. IRE sequences in the 3′UTR of the transferrin receptor mRNA protect the mRNA from degradation if the iron level is low. Iron is an essential element for many biological functions but ...
Under conditions of iron deficiency, iron regulatory proteins bind to the iron responsive element in the 5′ untranslated region of ferritin mRNA. This binding sterically prevents the recruitment of 43S translation pre-initiation complex and arrests translation of ferritin. On the other hand, binding...
产品名称:Iron-responsive element-binding protein 2 ELISA Kit 检测范围:0.312-20 ng/mL 保存条件:2-8℃低温保存 保质期:6个月,所有试剂盒均提供批次。 试剂盒成分:酶标板,试剂,标准品等。 选型: 产品规格:96T/48T 96T指可以做94个标本-2个标准对照-84个样本 48T指可以做47个标本-1个标准对照-42个样本...
iron-responsive-element网络铁离子调控序列网络释义 1. 铁离子调控序列 CsFtn核苷酸序列中含一环颈结构类似序列,与铁离子调控序列(iron-responsive element)相似。CsFtn多肽序列与其它吸虫铁蛋 …www.chemyq.com|基于1 个网页© 2025 Microsoft 隐私声明和 Cookie 法律声明 广告 帮助 反馈...
Iron responsive element RNA flexibility described by NMR and isotropic reorienta- tional eigenmode dynamics. J. Biomol. NMR. 32:179-193.Showalter, S.A., N.A. Baker, C. Tang and K.B. Hall, 2005. Iron responsive element RNA flexibility described by NMR and isotropic reorientational eigenmode...
To determine whether dietary protein affects the expression of the isoform of DMT1 that includes an iron responsive element (IRE), isoform-specific qPCR was performed using RNA isolated from the duodenum of rats consuming either a 20% (control) or 40% (high) protein diet for 1 wk. Rats on...
Some mRNA encoding proteins related to iron metabolism contain a specific stem-loop structure--iron responsive element (IRE)-in the 5' UTR. Binding of the ... Öjar Melefors - 《Biochem Biophys Res Commun》 被引量: 86发表: 1996年 加载更多来源...
Molecular basis for the recently described hereditary hyperferritinemia-cataract syndrome: a mutation in the iron-responsive element of ferritin L-subunit gene (the “Verona mutation”) . Blood 86 : 4050–4053, 1995.Girelli D, Corrocher R, Bisceglia L, Olivieri O, De Franceschi L, Zelante ...
A Mutation, in the Iron-Responsive Element of H Ferritin mRNA, Causing Autosomal Dominant Iron Overload[J] . Junji Kato,Koshi Fujikawa,Megumi Kanda,Nao Fukuda,Katsunori Sasaki,Tetsuji Takayama,Masayoshi Kobune,Kohichi Takada,Rishu Takimoto,Hirofumi Hamada,Tatsuru Ikeda,Yoshiro Niitsu.The American ...
We report the cloning and functional characterization of the iron responsive element (IRE) of human ferritin light (L) chain mRNA from a cDNA library of primary human T lymphocytes. Comparison of this palindromic cDNA element to the IRE predicted from the reported genomic sequence revealed significa...