Insulin induced gene 1, also known as INSIG1, is a protein encoded by the INSIG1 gene.Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. This gene i
Human Insulin-Induced Gene 1 Protein (INSIG1) ELISA Kit检测范围:0.313 ng/ml - 20 ng/ml 保存建议 4℃下运输。收到该Human Insulin-Induced Gene 1 Protein (INSIG1) ELISA Kit产品后,按照试剂盒手册中的储存说明储存试剂盒。 其他 Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白...
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Insulin-induced gene 1 (INSIG1) regulates sterol synthesis by mediating the activation of sterol regulatory element–binding protein (SREBP) and the degradation of the HMG-CoA reductase (HMGCR). INSIG1 is up-regulated during HIV-1 infection, but its role in HIV-1 infection is unknown. In ...
The INSIG were overexpressed using an adenovirus system with recombinant green fluorescent protein as the control. Downregulation of INSIG was performed via small interfering RNA targeting INSIG with a scrambled small interfering RNA as a negative control. The GMEC were treated with these constructs for...
protein stabilization of Insig-1, inhibition of cleavage and processing of SREBP-1, and lipogenic gene expression in response to metformin or A769662. AMPK-dependent phosphorylation ablates Insig’s interaction with E3 ubiquitin ligase gp78 and represses its ubiquitination and degradation, whereas ...
Insulin regulates metabolic activity, gene transcription, and cell growth by modulating the activity of several intracellular signaling pathways. Insulin activation of one mitogen-activated protein kinase cascade, the MEK/ERK kinase cascade, is well described. However, the effect of insulin on the paral...
In human hepatoma cell line Hep3B/T2, the human heat-shock-inducible gene hsp70 could be induced by insulin. The dose-dependent insulin effect correlates very well with the dissociation constant of the insulin receptor, indicating that the insulin effect is mediated by the insulin receptor. The ...
产品名称:Human Insulin-Induced Gene 2 Protein (INSIG2) ELISA Kit 产品型号:abx387997 产品展商:其它品牌 产品文档:无相关文档 简单介绍 Human Insulin-Induced Gene 2 Protein (INSIG2) ELISA Kit Human Insulin-Induced Gene 2 Protein (INSIG2) ELISA Kit的详细介绍 ...
胰岛素诱导基因 1 和 2 在猪前体脂肪细胞分化 过程的表达 朱亚南,李青莹,任书强,高妍,张嘉保 ,陈承祯 吉林大学动物科学学院,长春130062 摘要:为探讨胰岛素诱导基因1和2(Insig1,Insig2)在猪前体脂肪细胞中的表达规律,分离得到猪前体脂肪 细胞,并诱导分化,利用油红O染色提取法测定了细胞中的甘油三酯含量,同时采用...