Furthermore, ATF4 proactively upregulated the cell death-inducible gene expression, such as Chop, Chac1, and Trb3, thereby markedly reducing cell viability with 25HC. These findings support a model whereby that INSIGs sense an increase in oxysterol in the endoplasmic reticulum and induce an ...
Insulin induced gene 1, also known as INSIG1, is a protein encoded by the INSIG1 gene.Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. This gene i
Insulin-induced gene 1 (INSIG1) regulates sterol synthesis by mediating the activation of sterol regulatory element–binding protein (SREBP) and the degradation of the HMG-CoA reductase (HMGCR). INSIG1 is up-regulated during HIV-1 infection, but its role in HIV-1 infection is unknown. In ...
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4℃下运输。收到该Human Insulin-Induced Gene 1 Protein (INSIG1) ELISA Kit产品后,按照试剂盒手册中的储存说明储存试剂盒。 其他 Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白质供应商,致力于为生命科学、药物开发和生物技术领域的科学家和研究者提供最佳的客户体验和高质量的产品。产品...
胰岛素诱导基因 1 和 2 在猪前体脂肪细胞分化 过程的表达 朱亚南,李青莹,任书强,高妍,张嘉保 ,陈承祯 吉林大学动物科学学院,长春130062 摘要:为探讨胰岛素诱导基因1和2(Insig1,Insig2)在猪前体脂肪细胞中的表达规律,分离得到猪前体脂肪 细胞,并诱导分化,利用油红O染色提取法测定了细胞中的甘油三酯含量,同时采用...
Assistedreproductivetechnologies impairtheexpressionand methylationofinsulin-inducedgene1 andsterolregulatoryelement-binding factor1inthefetusandplacenta HangyingLou,M.D., a,b FangLe,M.D., a YingmingZheng,M.D., a LejunLi,M.D., a LiyaWang,Ph.D., a NingWang,M.D., a YiminZhu,M.D., a,b...
Insulin-induced gene (Insig) negatively regulates SREBP-mediated de novo fatty acid synthesis in the liver. However, the upstream regulation of Insig is incompletely understood. Here we report that AMPK interacts with and mediates phosphorylation of Insi
The present work examines the effect of inhibiting the p38 signaling pathway by use of specific inhibitors, either alone or in combination with insulin, on the activation of ERK1/2 and on the regulation of gene transcription in rat hepatoma cells. Activation of ERK1/2 was induced by insulin ...
产品名称:Human Insulin-Induced Gene 2 Protein (INSIG2) ELISA Kit 产品型号:abx387997 产品展商:其它品牌 产品文档:无相关文档 简单介绍 Human Insulin-Induced Gene 2 Protein (INSIG2) ELISA Kit Human Insulin-Induced Gene 2 Protein (INSIG2) ELISA Kit的详细介绍 ...