Insulin induced gene 1, also known as INSIG1, is a protein encoded by the INSIG1 gene.Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. This gene i
Insulin-induced gene 1 (INSIG1) regulates sterol synthesis by mediating the activation of sterol regulatory element–binding protein (SREBP) and the degradation of the HMG-CoA reductase (HMGCR). INSIG1 is up-regulated during HIV-1 infection, but its role in HIV-1 infection is unknown. In ...
Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progressionCarbon tetrachloride (CCl(4))De novo lipogenesis (DNL)Lipid remodellingLiver regenerationNon-alcoholic fatty liver disease (NAFLD)...
4℃下运输。收到该Human Insulin-Induced Gene 1 Protein (INSIG1) ELISA Kit产品后,按照试剂盒手册中的储存说明储存试剂盒。 其他 Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白质供应商,致力于为生命科学、药物开发和生物技术领域的科学家和研究者提供最佳的客户体验和高质量的产品。产品...
expressionofinsulininducedgenes12duringporcinepreadipocyte 系统标签: 胰岛素preadipocyte脂肪细胞porcine诱导 胰岛素诱导基因 1 和 2 在猪前体脂肪细胞分化 过程的表达 朱亚南,李青莹,任书强,高妍,张嘉保 ,陈承祯 吉林大学动物科学学院,长春130062 摘要:为探讨胰岛素诱导基因1和2(Insig1,Insig2)在猪前体脂肪细胞中的表...
Insulin-induced gene (Insig) negatively regulates SREBP-mediated de novo fatty acid synthesis in the liver. However, the upstream regulation of Insig is incompletely understood. Here we report that AMPK interacts with and mediates phosphorylation of Insi
胰岛素样生长因子-1与冠状动脉造影对照研究 2. Therapeutic effect of insulin-like growth factor-1 injection into the inner ears through scala tympani fenestration on gentamicin-induced hearing loss in guinea pigs; 鼓阶开窗微孔技术注入胰岛素样生长因子-1对庆大霉素致聋豚鼠的治疗作用 3. Protective effect...
combined data on cells expressing receptors with IR-ICD and IGF1R-ICD grown in DMEM+10% FBS. Data are shown as mean±s.e.m. (*P<0.05; **P<0.01. One-way ANOVA followed by Newman–Keulspost-hocanalysis,n=12). (f) Glycolysis induced by insulin or IGF-1 (100 nM) stimulation for...
elegans. WormBook: Online Rev C elegans Biol:1–31 Google Scholar Lithgow GJ, White TM, Melov S, Johnson TE (1995) Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress. Proc Natl Acad Sci U S A 92(16):7540–7544 Article CAS PubMed ...
Insulin-like growth factor-1 inhibits spreading depression-induced trigeminal calcitonin gene related peptide, oxidative stress & neuronal activation in ra... Furthermore, intranasal treatment with insulin-like growth factor-1 significantly reduced nave levels of trigeminal ganglion calcitonin gene related ...