In the present study, we sought mechanistic insights into how central nervous system-infiltrating monocytes program resident microglia to mediate angiogenesis and cerebrovascular repair after an intracerebral hemorrhage. In the penumbrae of human stroke brain lesions, we identified a subpopulation of ...
Microglia Activation Markers Molecules Secreted by VSMC Multiple Myeloma Multiple Sclerosis and Myelin Related Molecules Myeloid-derived Suppressor Cells (MDSC) Neuroinflammatory Factors Obesity Plasmacytoid Dendritic Cells Search Cytokine and Growth Factor Products ...
At the same time, deletion of IL-6 from microglia resulted in the increase of CCR6+ T cells and GM-CSF-producing T cells. Conversely, mice with IL-6 deficiency in the dendritic cells showed not only the previously described increase in the proportion of regulatory T cells and decrease in...
参考文献: Jin, Y., et al., Targeting polarized phenotype of microglia via IL6/JAK2/STAT3 signaling to reduce NSCLC brain metastasis. Signal Transduct Target Ther, 2022. 7(1): p. 52. 谢谢! 英拜生物 课题整包|甲基...
This is consistent with the finding that SMF promotes the elevation of IL-6 in microglia but inconsistent with the finding that SMF inhibits the reduction of IL-6 levels in LPS-stimulated microglia11. We believe that this difference is related to the fact that animal models and models of ...
Microglia Activation Markers Molecules Secreted by VSMC Multiple Myeloma Multiple Sclerosis and Myelin Related Molecules Myeloid-derived Suppressor Cells (MDSC) Neuroinflammatory Factors Obesity Plasmacytoid Dendritic Cells Search Cytokine and Growth Factor Products ...
in vivo IL-6Jose, S., et al. (2014). “Mesenchymal stem cells exert anti-proliferative effect on lipopolysaccharide-stimulated BV2 microglia by reducing tumour necrosis factor-alpha levels.” J Neuroinflammation 11: 149 neutralization in vivo IL-6Khmaladze, I., et al. (2014). “Mannan induc...
提出可以通过IL6/JAK2/STAT3信号通路调控小胶质细胞表型,探索了新的潜在的预防和治疗方法。 参考文献: Jin, Y., et al., Targeting polarized phenotype of microglia via IL6/JAK2/STAT3 signaling to reduce NSCLC brain metastasis. Signal Transduct Target Ther, 2022. 7(1): p. 52....
Yang, Hou, Feng, Li, Wang, Qin, Yang: "Lupus serum IgG induces microglia activation through Fc fragment dependent way and modulated by B-cell activating factor." in: Journal of translational medicine, Vol. 17, Issue 1, pp. 426, (2020) (PubMed). Aliases for IL-6 Antibodies interleukin...
本发明属于医学检测技术领域,涉及一种同时检测il-6、il-4和tnf-α的空心双金属试纸条及其制备方法。 背景技术: 神经炎症反应是脑缺血后造成脑组织损伤的最重要的病理生理机制之一。脑缺血后免疫炎症反应主要包括外周血中性粒细胞等白细胞在脑实质内的浸润,巨噬细胞(microphage)、小胶质细胞(microglia)等内源性炎性细...