11.Oxid Med Cell Longev2020:5146982.8. Li Q, et al.(2021) Microglia-derived interleukin-10 accelerates post-intracerebral hemorrhage hematoma clearance by regulating CD36.Brain Behav Immun94:437-457.9. Traustadottir GA, et al.(2019) The imprinted gene Delta like non-canonical Notch ligand 1 (...
Anat S, Isabelle S, Gal R F, et al. Interleukin-10 Prevents Pathological Microglia Hyperactivation following Peripheral Endotoxin Challenge. Immunity. 2020. -THE END- 新格元秉持“格物致知,识微通元”的创新性理念,致力于发展简便可...
Microglia are glial cells centrally related to pathophysiology and neuroimmunological regulation of pain through microglia–neuron crosstalk mechanisms. In contrast, anti-inflammatory mechanisms guided by immunological effectors such as IL-10 trigger the secretion of analgesic substances, culmin...
Microglia Homeostasis Molecules Secreted by VSMC Monocyte Markers Multiple Sclerosis and Myelin Related Molecules Myeloid-derived Suppressor Cells (MDSC) Natural Killer T (NKT) Cells Neuroinflammatory Factors Plasmacytoid Dendritic Cells Regulatory T Cells (Tregs) ...
and microglia. Neutralization of IL-17A following stroke reversed the worse outcome in IL-10 defcient mice and intracerebral treatment with recombinant IL-10 revealed that IL-10 controlled IL-17A positivelymphocytesin ischemic brains. Importantly, IL-10 acted diferentially on αβ and γδ T cells...
Microglia Homeostasis Molecules Secreted by VSMC Monocyte Markers Multiple Sclerosis and Myelin Related Molecules Myeloid-derived Suppressor Cells (MDSC) Natural Killer T (NKT) Cells Neuroinflammatory Factors Plasmacytoid Dendritic Cells Regulatory T Cells (Tregs) ...
4e, f). We did not observe increased microglia numbers in the Il-10-expressing αSyn-seeded mice relative to control αSyn-seeded mice in the spinal cord and the brain (Fig. 4a–h). Fig. 4: Intraspinal vIl-10 expression induces microgliosis but not astrogliosis in spinal cords of α...
Yang S, Gao L, Lu F, Wang B, Gao F, Zhu G, et al. Transcription factor myocyte enhancer factor 2D regulates interleukin-10 production in microglia to protect neuronal cells from inflammation-induced death. J Neuroinflammation. 2015;12:33. ...
(2015). Cerebral regulatory T cells restrain microglia/macrophage-mediated inflammatory responses via IL-10. Eur J Immunol 45, 180-191.Xie L, Choudhury GR, Winters A, Yang SH, Jin K. Cerebral regulatory T cells restrain microglia/macrophage-mediated inflammatory responses via IL-10. Eur J ...
Microglia Homeostasis Molecules Secreted by VSMC Monocyte Markers Multiple Sclerosis and Myelin Related Molecules Myeloid-derived Suppressor Cells (MDSC) Natural Killer T (NKT) Cells Neuroinflammatory Factors Plasmacytoid Dendritic Cells Regulatory T Cells (Tregs) ...