MicrogliaInterleukin (IL)-17-producing helper T cells may play a pivotal role in the pathogenesis of multiple sclerosis. Here, we examined the effects of IL-17 on microglia, which are known to be critically involved in multiple sclerosis. Treatment with IL-17 upregulated the microglial ...
We also found that IL-17 was produced by microglia in response to IL-23 or IL-1beta. Because microglia produce IL-1beta and IL-23, these cytokines may act in an autocrine manner to induce IL-17 expression in microglia, and thereby contribute to autoimmune diseases, such as MS, in the...
B Cell Chemotaxis, Migration, and Adhesion Cytokines and Receptors in Tfh Cell Differentiation and Function gamma delta T Cells Helper T (Th) Cells IL-17 Family LTi Cells Macrophage Activation Markers Microglia Activation Markers Molecules Secreted by VSMC ...
B Cell Chemotaxis, Migration, and Adhesion Cytokines and Receptors in Tfh Cell Differentiation and Function gamma delta T Cells Helper T (Th) Cells IL-17 Family LTi Cells Macrophage Activation Markers Microglia Activation Markers Molecules Secreted by VSMC ...
Mechanism of the immediate analgesic effect of the"three methods and three points"tuina technique based on the IL-17F/IL-17RC signaling pathway and M1 microglia 引用 收藏 分享 摘要 目的通过观察“三法三穴”推拿手法对轻型慢性压迫性损伤(minor CCI)模型大鼠脊髓背角中白细胞介素-17F(IL-17F)、白...
CNS Neuroscience & Therapeutics Negative regulation of glial Tim‐3 inhibits the secretion of inflammatory factors and modulates microglia to antiinflammatory phenotype after experimental intracerebral?… Pubmed: 30677253 OPEN ACCESS MACEDONIAN JOURNAL OF MEDICAL SCIENCES Seluang Fish (Rasbora Spp.) Oil De...
MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway. Nat Med 2011; 17: 64–70. Article CAS Google Scholar Zhu S, Pan W, Song X, Liu Y, Shao X, Tang Y et al. The microRNA miR-23b suppresses IL-17-associated ...
Administration of anti-IL17 for 5months, starting at the age of 7months, partially improved the cognitive abilities of the TS mice, reduced the expression of several pro-inflammatory cytokines and the density of activated microglia and normalized the APP and Aβ 1–42 levels in the hippocampi ...
found a clear association of Th17 and IL-17 with disease severity and progression. We summarize the recent advances made in correlating the presence of IL-17 with impaired blood–brain barrier integrity as well as the activation of astrocytes and microglia and the consequences for disease progressio...
gamma delta T Cells Helper T (Th) Cells IL-17 Family LTi Cells Macrophage Activation Markers Microglia Activation Markers Molecules Secreted by VSMC Multiple Sclerosis and Myelin Related Molecules Natural Killer T (NKT) Cells NCR-ILC3 Neuroinflammatory Factors ...