B Cell Markers Common gamma Chain Receptor Family Cytokines and Receptors in Tfh Cell Differentiation and Function Isolation, Culture, and Identification of Natural Killer Cells Natural Killer T (NKT) Cells Receptors in the Jak/STAT Pathway
IL-21 RECEPTORADAPTIVE IMMUNITYGATA3 EXPRESSIONIN-VIVOINTERLEUKIN-21NOTCHDIFFERENTIATIONACTIVATIONPlasmacytoid dendritic cells (pDCs) play a crucial role during innate immunity by secreting bulk amounts of type I interferons (IFNs) in response to Toll-like receptor (TLR)-mediated pathogen recognition. ...
Alternative Name:Interleukin-21 receptor; CD360; NILR Reactivity:Human (QC Testing) Isotype:Mouse BALB/c IgG1, κ Immunogen:Human IL-21R Transfected Cell Line Application:Flow cytometry (Routinely Tested) Vol. Per Test:5 µl Entre...
We have shown that virus-specific CD4 and CD8 memory T cells (TM) induce autophagy after T cell receptor (TCR) engagement to provide free glutamine and fatty acids, including in people living with HIV-1 (PLWH). These nutrients fuel mitochondrial ATP generation through glutaminolysis and fatty a...
Its private receptor, IL-21R, is expressed on T, B, and NK cells. Within the B cell lineage, IL-21 regulates IgG1 production and cooperates with IL-4 for the production of multiple Ab classes in vivo. IL-21R has been shown to activate the Janus kinase/signal transducers and ...
However, the role of IL-21/IL-21 receptor signaling plays in the pathogenesis of IBD is not very clear. In this study, using IL-21R.KO mice, we tested the role of IL-21/IL-21R signaling in the regulation of T helper cell responses during intestinal inflammation. Here we found that ...
5、malektr,castroi.interleukin-2receptorsignaling:attheinterfacebetweentoleranceandimmunity[j].immunity.2010;33(2):153–165. 6、rosannes,warrenj.l.interleukin-21:basicbiologyandimplicationsforcancerandautoimmunity[j].annu.rev.immunol.2008.26:57–79. ...
CD360 antigen; CD360; IL-21 R; IL-21 receptor; IL21R; IL-21R; interleukin 21 receptor; interleukin-21 receptor; MGC10967; NILR; Novel interleukin receptor Product Datasheets Product Datasheet COA SDS Related Research Areas B Cell Markers Common gamma Chain Receptor Family Cytokines and ...
To detect the targeting of PD-1Ab21 to tumor-specific T cells in vivo, we assessed PD-1-receptor occupancy by the injected PD-1Ab21 on OT-1 cells in the B16-OVA tumor model. OT-1 cells expressed high levels of PD-1 in vaccinated mice. At 30 min after the injection of PD-1Ab...
(1, 3 ‑ 5). Both IL-21 and IL-4 are necessary for efficient B cell IgG1 production and normal germinal center architecture (9). IL-21 engagement of the IL‑21 receptor on B cells induces Blimp-1 (which mediates plasma cell differentiation), and is important for memory responses (...