Conclusion: IL-18 promotes the proliferation of squamous cell carcinoma of the skin, it may be related to the down-regulation of TRPV4 and activation of Smad7 signaling pathway.金蝉王万卷李静吴惠林房秀萍Progress in Modern Biomedicine
et al. Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory. Proc. Natl. Acad. Sci. U. S. A. 107, 9777-9782, (2010). 23. Gattinoni, L. et al. Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem ...
signal transduction natural killer cell activation positive regulation of interferon-gamma production interleukin-18-mediated signaling pathway positive regulation of NF-kappaB import into nucleus T-helper 1 cell differentiation 问题与答案 2 Answer I received my product without ice. Does the antibody guar...
Upon binding, IL-18 activates NF-κB and AP-1 via TRAF6 signaling pathway3, 4. 1. Yasuda K. et al., 2019. Interleukin-18 in health and disease. Int J Mol Sci. 20(3). 2. Dinarello CA. et al., 1998. Overview of interleukin-18: more than an interferon- gamma inducing factor...
Astragalus polysaccharide RAP induces macrophage phenotype polarization to M1 via the notch signaling pathway. Molecules. 2019;24:2016. Article CAS PubMed Central Google Scholar Tron'ko N, Zak K. [Obesity and diabetes mellitus]. Likars’ka sprava. 2013;8:3–21. Google Scholar Zhou H, ...
signaling pathwayactivation of protein kinase B activityinterferon-gamma productioninterleukin-6 productionpositive regulation of granulocyte macrophage colony-stimulating factor productionpositive regulation of interferon-gamma productionpositive regulation of interleukin-17 productionpositive regulation of natural ...
Key Words: JAK/STAT pathway; Interleukin-18;Acute pancreatitis;Kupffer cel ls; Liver injury Li ML(Zhu RM)Zhang XH(Shi W)Yang MF( Ji HZ)Guo JY Role of JAK/STAT signaling pathway in pancreatic elastase-induced secretion of interleukin-18 within rat Kupffer cells Shijie Huaren Xiaohua Zazhi 20...
Thus, in the current study, we tested our hypotheses that the IL-18 inflammatory signal pathway plays a key role in radiation-induced cell and tissue damage and dysfunction. IL-18BP counters IL-18 activation and therefore may mitigate/treat IL-18-mediated multi-organ injury and increase ...
功能 interleukin-18 receptor activity transmembrane signal receptor 参与通路 signal transduction natural killer cell activation positive regulation of interferon-gamma production interleukin-18-mediated signaling pathway positive regulation of NF-kappaB import into nucleus T-helper 1 cell differentiation 问题...
in pathways related to M1 macrophage activation or pathways related to inhibition of M2 macrophages, such as the IL-17 signaling pathway [14], TNF signaling pathway [15], p53 signaling pathway [16], and Toll-like receptor signaling pathway (Fig.2B) [17], We found that the GFPT2 knockdown...