题目:Interleukin-18 signaling promotes activation of hepatic stellate cells in murine liver fibrosis 译名:IL-18信号通路促进小鼠肝纤维化中肝星状细胞的激活 期刊:Hepatology IF:17.30 发表时间:2022.9.4 通讯作者单位:德国夏瑞蒂医科大学 DOI号:doi.org/10.1002/hep.327 主要内容细胞因子白细胞介素18 (IL-18...
1 | Regulation of the IL-18 signaling axis in the TME. 然而,一项2009年的重组人源IL-18用于治疗转移性黑色素瘤的Ⅱ期临床试验结果显示:IL-18的临床治疗效果十分有限[14]。2018年,已有文献显示在多发性骨髓瘤中,高水平的IL-18将导致免疫抑制性的MDSC浸润,并与肿瘤的不良预后相关[15]。而Aaron Ring研究...
2023年7月27日斯克里普斯研究所分子医学系Marisa Roberto研究团队在Cells发表论文“IL-18 Signaling in the Rat Central Amygdala is Disrupted in aComorbid Model of Post-Traumatic Stress and AlcoholUse Disorder”,揭示了在创伤后应激和酒精使用障碍的共病模型中,大鼠中央杏仁核中的IL-18信号被破坏。 酒精使用障碍...
题目:Interleukin-18 signaling promotes activation of hepatic stellate cells in murine liver fibrosis 译名:IL-18信号通路促进小鼠肝纤维化中肝星状细胞的激活 期刊:Hepatology IF:17.30 发表时间:2022.9.4 通讯作者单位:德国夏瑞蒂医科大...
河南省肾脏病研究中心主任、郑州大学第一附属医院刘章锁教授为共同通讯作者的文章“IL18 signaling causes islet β cell development and insulin secretion via different receptors on acinar and β cells”、“Differential IL18 signaling via IL18 receptorand Na-Cl co-transporter discriminatingthermogenesis and glu...
Interleukin-18 (IL18) is a cytokine playing a role in T-cell polarization, but also for regulating energy homeostasis via the dimeric IL18 receptor (IL18r) and Na-Cl co-transporter (NCC) on adipocytes. Here we show that IL18 signaling in metabolism is regulated at the level of receptor ...
[4].Anticytokine Agents Targeting Interleukin Signaling Pathways for the Treatment of Atherothrombosis. [5].IL-18 and skin inflammation. [6].The role of interleukin-18 in pancreatitis and pancreatic cancer. [7].IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections....
InflammationDependent IL18 Signaling Restricts Hepatocellular Carcinoma Growth by Enhancing the Accumulation and Activity of Tumor-Infiltrating Lymphocytes. Cancer Res 2016;76:2394-405.19. Wong JL, Berk E, Edwards RP, et al. ...
Reference:[1].Interleukin-18 in Health and Disease.[2].Unique Action of interleukin-18 on T Cells and Other immune Cells.[3].IL-18 and Cutaneous Inflammatory Diseases.[4].Anticytokine Agents Targeting Interleukin Signaling Pathways for the Treatment of Atherothrombosis.[5].IL-18 and skin infla...
[4].Anticytokine Agents Targeting Interleukin Signaling Pathways for the Treatment of Atherothrombosis. [5].IL-18 and skin inflammation. [6].The role of interleukin-18 in pancreatitis and pancreatic cancer. [7].IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections....