IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells. Cancer Res. 2011;71:5296-306.Fernando RI, Castillo MD, Litzinger M, Hamilton DH, Palena C. IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of hum...
Signaling ways信号通路 IL-8刺激CXCR1和/或CXCR2受体后,激活异源三聚体小G蛋白后,IL-8信号传导促进主要效应子(PI3-K)或磷脂酶C活化,从而促进Akt,PKC,钙动员和/或MAPK信号传导级联反应的活化。这些信号通路已显示出可促进蛋白质翻译(左)并调节一系列转录因子的活性(下)。 对...
IL-8 signaling is up-regulated in alcoholic hepatitis and DDC fed mice with Mallory Denk Bodies (MDBs) presentdoi:10.1016/j.yexmp.2015.08.002Mallory–DenkBodiesAlcoholichepatitisIL-8signalingCXCR2Chemokines and their receptors are involved in oncogenesis and in tumor progression, invasion, and ...
Targeting IL-8 signaling in combination with ICB delayed the onset of castration resistance and increased the density of polyfunctional CD8 T cells in tumors. Our findings establish a novel mechanism by which castration mediates IL-8 secretion and subsequent PMN-MDSC infiltration, and highlight ...
IL-8-stimulated neutrophil adhesion was inhibited 50% by bisindolylmaleimide-I, implicating protein kinase C (PKC) in the intracellular signaling from the IL-8R to Mac-1. A 74-kDa molecular mass species was detected by an activation-specific Ab to PKC when cells were stimulated with PMA or ...
signaling pathway. The comparison of CON and DON showed no “uniquely” genes in the DON group. Furthermore, CON vs. LPS resulted in 263 “uniquely” genes, which can be related to different pathways: (1) osteoclast differentiation, (2) PPAR signaling pathway, (3) FoxO signaling pathway, ...
Fernando RI, Castillo MD, Litzinger M, Hamilton DH, Palena C (2011) IL-8 signaling plays a critical role in the epithelial–mesenchymal transition of human carcinoma cells. Cancer Res 71 (15): 5296–5306. Article CAS Google Scholar Freund A, Chauveau C, Brouillet JP, Lucas A, Lacroix...
Int6/eIF3e silenced HIF2α stabilization enhances migration and tube formation of HUVECs via IL-6 and IL-8 signaling 来自 Semantic Scholar 喜欢 0 阅读量: 96 作者:A Endler,L Chen,Q Li,K Uchida,T Hashimoto,L Lu,GT Xu,F Shibasaki ...
signaling pathway positive regulation of angiogenesis embryonic digestive tract development induction of positive chemotaxis chemokine-mediated signaling pathway cellular response to lipopolysaccharide cellular response to interleukin-1 cellular response to tumor necrosis factor positive regulation of neutrophil ...
Tween-TBS and bound primary antibodies were detected with Peroxidase-conjugated goat anti-rabbit antibodies (Cell signaling technology) using the ECL detection system (BioRad) and a Chemdoc image analyzer (BioRad). Statistics The mean values±s.e.m. were calculated and plotted using GraphPad ...