The analytic sample comprised 688 racially diverse YMSM aged 16–29 (M = 22.9 years) living in Chicago, IL (19.2% living with HIV). Using multivariable logistic regression, we examined longitudinal associations between condom-associated sexual functioning (erectile function, orgasm satisfaction, ...
Earlier work demonstrated that the proliferative, survival, and angiogenic effects of IL-6 on epithelial cells are mediated by the STAT3 pathway17,18. Activation of STAT3, an IL-6-responsive transcription factor, was shown to induce tumor-promoting inflammation as well as activate canonical oncogenic...
(B) Supernatant concentrations of TNF-α, IL-10 and IL-6 were determined 12 h after the 100 ng/mL LPS challenge (n = 10). (C) TNF-α mRNA expression was measured at 2 h after the LPS challenge (n = 8). (D) Monocyte surface HLA-DR expression was measured after 16 h...
Collectively, these data demonstrate that modulation of IL-13 signaling may be a suitable pathway for anti-fibrotic therapeutic intervention. T helper 17 lymphocytes (Th17) are another distinct subset of pro-inflammatory cells that have been associated with fibrosis in various tissues, including the ...
showed that IFN-γ upregulates H4R expression on inflammatory DCs of AD patients and H4R stimulation of these cells leads to reductions in TNF-α and IL-12 secretion [46]. In a CHS model which displays some features of AD, blocking of the H4R led to decreased DC migration to the LNs...
Oxidation Resistance 1 (OXR1) gene is a highly conserved gene of the TLDc domain-containing family. OXR1 is involved in fundamental biological and cellular processes, including DNA damage response, antioxidant pathways, cell cycle, neuronal protection, a
The declaration should include the length, such as fixed char id[8]. You can't use fixed char id[].How to use pointers to copy an array of bytesThe following example uses pointers to copy bytes from one array to another.This example uses the unsafe keyword, which enables you to use ...
Since these auto-regulatory T cells express IL-2Rβ (CD122), we hypothesized that their development might also be regulated by IL-2. Here, we investigate the effects of differences in IL-2 expression on this autoregulatory subset. We show that decreased IL-2 production impairs the regulatory...
Craft1, Serena L. M. Craft1 & Cuong Q. Nguyen1,2 Interleukin (IL)-17 is one of the critical inflammatory cytokines that plays a direct role in development of Sjögren's syndrome (SjS), a systemic autoimmune disease characterized by a progressive chronic attack against the ...
A study indicating that MSC-derived CAFs promote inflammation-induced gastric cancer progression and are characterized by global DNA hypomethylation and elevated expression of IL-6, WNT5A and bone morphogenetic protein 4 (BMP4). CAS PubMed PubMed Central Google Scholar Xu, J. et al. ...