典型通路报告期6 signalingil 6信号.pdf,Canonical Pathway Report Date: 2016-02-14 Report Version: FFFF.svnRevision FFFF Content Version: 26127183 (Release Date: 2015-11-30) Canonical IL-6 Signaling Pathway Description Interleukin 6 (IL-6) is considered a r
IL‐6 Signaling is Required for LPS‐induced Barrier Function Lossdoi:10.1096/fasebj.2022.36.S1.R5104Lu, ShuhanMartino, NinaChuy, DareenRamos, Ramon B.Adam, Alejandro P.FASEB Journal
IL-6 trans-signaling-dependent rapid development of cytotoxic CD8+ T cell function. Cell Rep. 2014;8:1318–27. Article PubMed CAS Google Scholar McLoughlin RM, Jenkins BJ, Grail D, Williams AS, Fielding CA, Parker CR, et al. IL-6 trans-signaling via STAT3 directs T cell infiltration...
Treg功能的获得可恢复IL6Ra TKO小鼠受损的肌肉修复。值得注意的是,在WT小鼠中对IL6R的药理阻断可以在IL6Ra TKO小鼠中发现肌肉功能缺陷,从而突出了这一发现的临床意义。 论文ID 题目:Regulatory T cells require IL6 receptor alphasig...
Stress-induced IL-6 requires consciousness and beta-3-adrenergic-receptor signaling in brown adipocytes. IL-6 is required for stress hyperglycemia, a metabolic adaptation that enables the “fight or flight” response, via hepatic gluconeogenesis. The cost of stress-induced IL-6 is that it ...
近日,来自德国German Research Center for Environmental Health的Carolin Daniel研究组在Cell Metabolism上发表题为Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration的文章,就上述...
IL-6 Transsignaling Promotes PanIN Progression Based on these findings, we hypothesized that Stat3 activation in pancreatic oncogenesis depends on the microenvironment, particularly on myeloid cells that secrete the gp130 ligand IL-6. To examine the interaction between macrophages and acinar cells that...
IL-6 signaling results in the phosphorylation and activation of STAT3 leading to hepatoprotection.(33) Studies using hepatocyte-specific deletion of STAT3 have demonstrated a protective function of STAT3 in ethanol-induced fatty liver and CCl4-induced liver injury.(34, 35) We hypothesize that the ...
Ex Vivo Expansion of CD4+CD25+FoxP3+ T Regulatory Cells Based on Synergy between IL-2 and 4-1BB Signaling Naturally occurring CD4+CD25+FoxP3+ T regulatory (Treg) cells require three distinct signals transduced via TCR, CD28, and IL-2R for their development and ... KG Elpek,ES Yolcu,...
Cell Signaling Technology'sIL-6 (D5W4V) XP ® Rabbit mAbis a Rabbit monoclonal antibody. TheIL-6 (D5W4V) XP ® Rabbit mAb Antibodywas generated using IL6, and Interleukin 6 as the antigen. It reacts with Mouse. This antibody has been shown to work in applicatio...