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近日,来自耶鲁大学药学院的Andrew Wang 研究团队在Cell上发表了题为Origin and Function of Stress-Induced IL-6 in Murine Models的研究,揭示了应激状态产生的IL-6的主要来源是棕色脂肪组织,并阐明了IL-6水平升高的重要的生理学意义。 作者发现,与之前报道一致,小鼠在不同的压力刺激下 (如更换笼子,社交隔离等) ...
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5.Qing H, Desrouleaux R, Israni-Winger K, et al. Origin and Function of Stress-Induced IL-6 in Murine Models [published correction appears in Cell. 2020 Sep 17;182(6):1660].?Cell. 2020;182(2):372-387.e14. doi:10.1016/j.cell.2020.05.054 ...
Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It...
每一条链的羧基端包含在抗 体效应子功能(antibodyeffectorfunction)中起主要作用的恒定区。人轻链的种类被 称为kappa和lambda轻链。重链种类为mu、delta、gamma、alpha或epsilon,并定义了抗 体的同种型。抗体的同种型分别为181、1§0、1§6、1 §4和1§￡。在轻链和重链中,可变区和 恒定区通过约12或更多个...
[27] Han, Hui,et al."Oncostatin M promotes infarct repair and improves cardiac function after myocardial infarction." American journal of translational research 13.10 (2021): 11329. [28] Richards, Carl D. "The enigmatic cytokine oncostatin m and roles in disease." International Scholarly Research...