1. Akdis, M., Burgler, S., Crameri, R., Eiwegger, T., Fujita, H., Gomez, E., ... & Rhyner, C. (2011). Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases. Journal of allergy and clinical immunology, 127(3), 701-721. ...
Functions of IL-6 (2)Immune response (2)Hematopoiesis (3)Acute phase response (3)Nerve system (3)IL-6 and disease (4)诊断价值 (5)1980年白介素-6（interleukin 6, IL-6）被Weissenbach发现，命名为β2 干扰素，在之后的研究中IL-6不断被其他人发现并先后命名为杂交瘤/浆细胞瘤生长因子、B 细胞...
Moreover, anti-IL-6 antiserum specifically inhibited the in vitro tumor growth. All data indicated that IL-6 functions as an in vitro autocrine growth factor of renal cell carcinomas.doi:10.1016/0014-5793(89)80805-1John Wiley & Sons, LtdFEBS Letters...
[17] Rojas-Zuleta WG, et al. Th9 lymphocytes: a recent history from IL-9 to its potential role in rheumatic diseases. Autoimmunity reviews. 2016 Jul 1;15(7):649-55. [18] Noelle RJ, et al. Cellular sources and immune functions of interleukin-9. Nature Reviews Immunology. 2010 Oct;10...
[7]https://microbenotes.com/immunoglobulin-g-igg-structure-subclasses-and-functions/ [8]https://absoluteantibody.com/antibody-resources/antibody-overview/antibody-structure/ [9]Tugizova M, Vlahovic L, Tomczak A, et al. ...
9. Zaiss, D.M.W., Gause, W.C., Osborne, L.C., and Artis, D. (2015). Emerging functions of amphiregulin in orchestrating immunity, inflammation, and tis- sue repair.Immunity42, 216–226. https://doi.org/10....
The PI3K/Akt/NF-KappaB cascade activated by IL-6, functions cooperatively to achieve the maximal anti-apoptotic effect of IL-6 against TGF-Beta (Transforming Growth Factor-Beta). The anti-apoptotic mechanism of PI3K/Akt is attributed to phosphorylation of the BCL2 ...
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of ...
Background:This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites ...
Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase ...