However, while it is being eliminated, other B cells for the disease clone themselves but do not generate antibodies. This second set of B cells remains in your body for years, so if the disease reappears your body is able to eliminate it immediately before it can do anything to you. A...
Hence, we designed a "label-free" electrochemical immunosensor based on G-Chi-Au/PtNP nanocomposites in this work. In addition, effective immobilization of antibodies is an essential step in constructing electrochemical immunosensors and constitute another important factor in improving the performance of...
Peripheral tolerance is associated with suppression of the production of self-reactive antibodies by B cells and inhibition of self-reactive effector T cells, such as cytotoxic T lymphocytes. The actions of regulatory T cells constitute one mechanism of peripheral tolerance. Type 1 diabetes A chronic...
Conversely, if you are looking for an antibody to work in other species, use a polyclonal antibody against a recombinant, long-length protein. 95% of Proteintech's antibodies are raised against recombinant, long-length human proteins, meaning that they have an increased chance of cross-reactivity...
A further eight women with a history of genital herpes had antibodies to HSV-1 only. DISCUSSION This is the first time that the seroprevalence of HSV-1 and HSV-2 has been described in female sex workers in Europe. Compared with previous studies of un- selected patients attending sexually ...
et al. Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans. J. Clin. Invest. 119, 1335–1349 (2009). Article CAS PubMed PubMed Central Google Scholar Nus, M. et al. Marginal zone B cells control the response of follicular helper T cells to ...
IL-17 and a pro-inflammatory response (E). A higher production of B cell activation factor (BAFF) leads to a prolonged survival of autoreactive B cells, which secrete interleukin (IL)-6 and 10, turn into plasma cells and produce auto-antibodies (F). Macrophages are activated, producing ...
However, while it is being eliminated, other B cells for the disease clone themselves but do not generate antibodies. This second set of B cells remains in your body for years, so if the disease reappears your body is able to eliminate it immediately before it can do anything to you. A...
Intravenous immunoglobulin (IVIG) preparations comprise pooled IgG antibodies from the serum of thousands of donors and were initially used as an IgG replacement therapy in immunocompromised patients. Since the discovery, more than 30 years ago, that IVIG therapy can ameliorate immune thrombocytopenia, ...
Chronic infection: why do CD4 cells die? After the intense few weeks of acute infection, the body begins to produce antibodies and immune cells that specifically target HIV. During this period (known as seroconversion), viral load levels drop and the CD4 cell count returns to near-normal level...