Antibody 抗原 Recombinant human IL-6. 偶联物 Unconjugated 形式 Liquid 浓度 1.0 mg/mL 纯化类型 Protein G 保存液 PBS 内含物 no preservative 保存条件 -20°C 运输条件 Ambient (domestic); Wet ice (international) RRID AB_223481 产品详细信息 P620 detects IL-6 in WB...
Antibody 克隆号 7IL6 抗原 Recombinant human IL-6. 偶联物 Biotin 形式 Liquid 浓度 0.5 mg/mL 纯化类型 Protein G 保存液 PBS with 4% BSA 内含物 proprietary Preservative 保存条件 -20°C 运输条件 Ambient (domestic); Wet ice (international) RRID AB_223577 产品详...
Anti-interleukin-6 monoclonal antibody、Chimeric anti-interleukin-6 monoclonal antibody、Siltuximab (USAN/INN) + [6] 靶点 IL-6 作用机制 IL-6抑制剂(白细胞介素-6抑制剂) 治疗领域 免疫系统疾病血液及淋巴系统疾病其他疾病+ [7] 在研适应症
In rats with induced endometriosis, anti-IL-6 receptor monoclonal antibodies could offer a new horizon of usage of this immune-modulatory biologic drug, used in other autoimmune diseases, in treatment of endometriosis.doi:10.1007/s12026-020-09153-5Ahmed A El-Zayadi...
Tocilizumab (Anti-Human IL6R) is a neutralizing antibody against human interleukin-6 receptor (IL-6R) that blocks the binding of IL-6 to IL-6R, thereby inhibiting both classical and trans signaling. It can be used to study rheumatoid arthritis and has been suggested as a possible drug for ...
IL-6是趋化因子家族成员之一,主要由单核巨噬细胞、血管内皮细胞等生成,其作用靶细胞较多,是一种具有复杂生理功能的细胞因子,并在RA等慢性炎症过程中扮演重要角色。IL-6不仅可以打破成骨细胞与破骨细胞的平衡状态,导致患者骨质疏松;还可以与受体以及其他细胞因子相...
OSM Recombinant Monoclonal Antibody (Code: CSB-RA017260MA1HU)参考文献：[1] Tanaka, Toshio, Masashi Narazaki, and Tadamitsu Kishimoto. "Interleukin (IL-6) immunotherapy." cold spring harbor perspectives in biology 10.8 ( 2018): a028456.[2] Jones, Simon A., Jürgen Scheller, and Stefan ...
OSM Recombinant Monoclonal Antibody (Code: CSB-RA017260MA1HU) 参考文献: [1] Tanaka, Toshio, Masashi Narazaki, and Tadamitsu Kishimoto. "Interleukin (IL-6) immunotherapy." cold spring harbor perspectives in biology 10.8 ( 2018): a028456. ...
3. Clazakizumab:一款靶向IL-6的人源化单抗。最早由Alder公司研发,BMS曾经license-in全球权益,后来又在2014年把权益还给了Alder。紧接着在2016年5月,Alder再次出让全球权益,这次把Clazakizumab授权给了一家2016年初成立的加拿大药企Vitaeris,进行针对抗体介导的排斥反应(Antibody-mediated Rejection)的研发。
OSM Recombinant Monoclonal Antibody (Code: CSB-RA017260MA1HU) 参考文献: [1] Tanaka, Toshio, Masashi Narazaki, and Tadamitsu Kishimoto. "Interleukin (IL-6) immunotherapy." cold spring harbor perspectives in biology 10.8 ( 2018): a028456. ...