A potent and specific neutralizing mAb against hIL-6 Provided azide-free No cross-reactivity with murine IL-6 Each lot is functionally tested References: 1. Kang S. et al., 2015.Therapeutic uses of anti-interleukin-6 receptor antibody. Int. Immunol. 27: 21-9. ...
Interleukin-6 neutralizing antibody attenuates the hypersecretion of airway mucus via inducing the nuclear translocation of Nrf2 in chronic obstructive pulmonary disease. See more citations NeutraKine® IL-12/IL-23 p40 Monoclonal antibody 69006-1-Ig ...
Neutralization -The neutralization activity of IL6 Neutralizing Antibody is measured by its ability to neutralize IL6 induced proliferation in the T1165 mouse plasmacytoma cell line. The antibody Neutralizing Titer (IC50) is typically 20.5-82 ng/mL in the presence of 10 ng/mL Recombinant Human IL...
Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity. This antibody is a neutralizing control antibody for IL-6, the immunogen is the same as Neutrakine 69001-1-...
administration of IL-6 neutralizing antibody, normal goat or normal rat IgG on mechanical allodynia associated with L5 spinal nerve transection were compared. Spinal glial activation was assessed at day 10 post surgery by immunohistochemistry. Low dose (0.01–0.001 μg) goat anti-rat IL-6 i.t....
Applications Reported: The MQ2-13A5 antibody has been reported for use in capture of human IL-6 by ELISA, intracellular staining for flow cytometric analysis, and for neutralizing IL-6 bioactivity. Applications Tested: The MQ2-13A5 antibody has been tested as the capture antibody in a sandwich...
and IL-6R neutralizing antibody blocked PKCβⅡ overexpression-induced invasion of HCC cells (P<0.01). The protein level of P-STAT3 increased significantly upon PKCβⅡ overexpression (P<0.05). Immunohistochemical analysis...
IL-6 Neutralizing Antibody 英文别名: IL-6 Neutralizing Antibody 中文名: 中文别名: CBNumber: CB66196808 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商1 IL-6 Neutralizing Antibody化学性质 安全信息 IL-6 Neutralizing Antibody性质、用途与生产工艺 ...
[20] West, Nathaniel R., et al. "Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease." Nature medicine 23.5 (2017): 579-589.[21] Ito, Hiroaki. "IL-6 and Crohn's disease." Current Drug ...
InvivoGen provides this antibody in two grades: In vitrouse:Anti-mIL-6-mIgG1e3 In vivouse:Anti-mIL-6-mIgG1e3 InvivoFit™ AllInvivoFit™products are handled in a clean room, filter-sterilized, and tested for bacterial contaminants. Additionally, this grade guarantees low levels of endotoxi...