Recombinant murinized IL-6 antibody InvivoGen provides arecombinantmuninized anti-mouse IL-6-mIgG1e3monoclonal antibody (mAb) that was previously extracted from hybridoma. It is now expressed and produced in Chinese hamster ovary (CHO) cells, ensuring reliability and lot-to-lot reproducibility. Th...
Manolagas, S.C.Bone & MineralJilka RL, Girasole G, Passeri G, Williams D, Abrams J, Manolagas SC. Interleukin-6 neutralizing antibody administration prevents osteoclastogenic response to ovariectomy in the mouse. In: Proceedings of the XIth international conference on calcium regulating hormones...
When the mice were treated with neutralizing monoclonal antibody to IFN-γ, the growth rate of immunogenic sarcomas transplanted into mice was greater than the growth rate in the control mice (Dighe et al., 1994). Further, overexpression of the truncated dominant negative form of the murine IFN...
We hypothesized that IL-11 might play a role in vessel hyperplasia and investigated the effects of the neutralizing IL-11 antibody (X203) or an isotype control IgG antibody in a carotid wire-induced endothelial injury mouse model. Material and methods All experiments and methods were performed ...
Assessment of neutralizing antibody and HI antibody titers in HA1-Fc- and HA1-Fdc-vaccinated mouse sera.Lanying DuVirtual HoChuen LeungXiujuan ZhangJie ZhouMin ChenWu HeHaiYing ZhangChris C. S. ChanVincent KwokMan PoonGuangyu Zhao
Increased in vivo antibody activity against interferon alpha, interleukin- 1alpha, and interleukin-6 after high-dose Ig therapy. Blood 1997;90:2376– 80. 39. Ross C, Svenson M, Hansen MB, Vejlsgaard GL, Bendtzen K. High avidity IFN-neutralizing antibodies in pharmaceutically ...
Neutralizing monoclonal antibody against murine IL-1α InvivoGen provides arecombinantfully mouse anti-mouse IL-1α-mIgG1monoclonal antibody (mAb) that was previously extracted from hybridoma. It is now expressed and produced in Chinese hamster ovary (CHO) cells, ensuring reliability and lot-to-lo...
possibly through the imbalances of neural circuitry and impairments ofsynaptic plasticity. In this study, we evaluate whether inhibiting IL-6 signaling in the brain is sufficient to modulate the autism-like behaviors on the BTBR mice. The results showed that chronic infusion of an analog of the ...
Human Anti-Mouse Antibody (HAMA) refers to a minimal immune response that occurs in humans after the administration of murine antibodies. HAMA response is reduced in a specific type of monoclonal antibody. AI generated definition based on: Animal Biotechnology, 2014 ...
For example, injection with an EV71-specific neutralizing antibody before or after infection, can strongly reduce lethality and tissue viral loads of a mouse-adapted strain M2 in a B cell-deficient C57BL/6-derived mouse model [44]. In another example, NOD/SCID mice deficient in T and B ...