IL-22 activates the STAT3 signaling pathway in GBM cell lines.Hussein AkilAmazigh AbbaciFabrice LallouéBarbara BessetteLéa M. M. CostesLinda DomballeSandrine CharreauKarline GuilloteauLucie KarayanTaponFrançoisXavier Bernard
The changed Trp metabolism by pectin supplementation activated the AhR/IL-22/STAT3 signaling pathway in jejunal mucosa of piglets Microbial derived tryptophan catabolites (indole compounds) are ligands for the AhR and act on the AhR in lymphoid cells. Therefore, we investigated the effect of pectin ...
Several components of mucosal immunity are disrupted in CD. These include epithelial barrier integrity, mucous production and cell turnover, the production of antimicrobial peptides and proteins (AMPs), and the release of metal ion scavengers that contribute to nutritional immunity21,22,23. Nutritional...
ConclusionsIL⁃33 promotes ILC2 and macrophage recruitment during peritoneal sepsis. And the recruitment of peritoneal ILC2 depends on IL⁃33/ST2 signaling pathway. Peritoneal ILC2 derived cytokines IL⁃9 and IL⁃13 e...
发布时间:2019-08-03 23:19 原文链接: IL17SignalingPathway Inflammation is a complex response involving many different cells and signaling molecules, including the secretion of the cytokine IL-17 by activated T cells. IL-17 secretion is restricted to specific subsets of T cells but the receptor ...
ZHAO Wenting, JIANG Honghong, GU Yunfan, et al. Fangji Dihuang formulation ameliorated DNCB-induced atopic dermatitis-like skin lesions by IL-17 signaling pathway: integrating network analysis and experimentalvalidation[J]. Frontiers in Pharmacology, 2023, 14: 1220945. ...
Binding of IL-22 to its receptor complex induces signal transduction, particularly via the JAK-STAT pathway. In addition to the membrane-bound IL-22R1/IL-10R2 complex, a soluble single-chain IL-22 receptor termed IL-22BP has been found to antagonize IL-22 binding and signaling. IL-22 ...
secret IL-27 to take effect on the HBE cells, which might form a positive feedback cycle. Finally, preventative IL-27’s effects were mediated by reversing the impairment of the signal transducer and activator of transc...
et al. Lactobacillus accelerates ISCs regeneration to protect the integrity of intestinal mucosa through activation of STAT3 signaling pathway induced by LPLs secretion of IL-22. Cell Death Differ 25, 1657–1670 (2018). https://doi.org/10.1038/s41418-018-0070-2 Download citation Received07 June...
IL-17 signaling pathway has an ethnicity-specific effect in LSCC where it is upregulated in the Chinese while not in the Caucasians and IL17RC might play a key role. Targeting genes located in the IL-17 signaling pathway may be beneficial for Chinese LSCC patients. 展开 关键词: IL-17 ...