Because the regenerative capacity of cardiac tissue is limited, human pluripotent stem cells (hPSCs) have emerged as a potential source for cellular-based therapies. However, for these therapies to be effective, sufficient numbers of differentiated cells must be produced and properly sorted, ...
TransStemTMChemically Defined Xeno-free Human Pluripotent Stem Cell Medium是一种化学成分明确的、无动物源性成分、且无需滋养层细胞的人多能性干细胞(Human Pluripotent Stem Cells, hPSCs)完全培养基。本产品稳定性好,支持hPSCs的快速增殖,能够长期维持hPSCs的自我更新和分化潜能。
In this study, we generated alveolar organoids (AOs) derived from human pluripotent stem cells (hPSCs) for use as an PF model and for drug efficacy evaluation. Stepwise direct differentiation of hPSCs into alveolar epithelial cells by mimicking developmental cues in a temporally controlled manner ...
The ability to generate human pluripotent stem cells (hPSCs) holds great promise for the understanding and the treatment of human neurological diseases in modern medicine. The hPSCs are considered for theirin vitrouse as research tools to provide relevant cellular model for human diseases, drug disco...
Human pluripotent stem cells (hPSCs)-derived cardiomyocytes (hPSC-CMs) represent a potential indefinite cell supply for cardiac tissue engineering and poss... X Sun,SS Nunes - 《Nature Methods》 被引量: 247发表: 2016年 Engineering Adolescence: Maturation of Human Pluripotent Stem Cell-Derived Cardi...
Culture conditions play an important role in regulating the genomic integrity of Human Pluripotent Stem Cells (HPSCs). We report that HPSCs cultured in Essential 8 (E8) and mTeSR, two widely used media for feeder-free culturing of HPSCs, had many fold higher levels of ROS and higher mitochondr...
The use of human pluripotent stem cells (hPSCs) in biomedical research is expanding exponentially. hPSCs provide an excellent system for studying basic human development and function, as well as providing a robust platform for testing stem cell-based therapies in the laboratory and clinical settings....
Directed differentiation of human pluripotent stem cells (hPSCs) has the potential to produce human cell types that can be used for disease modeling and cell transplantation. Two key challenges in the differentiation from hPSCs to beta cells are the specification from pancreatic progenitors to insulin...
Human pluripotent stem cells for disease modelling and drug screening Considerable hope surrounds the use of disease-specific pluripotent stem cells to generate models of human disease allowing exploration of pathological mec... Y Maury,M Gauthier,M Peschanski,... - 《Bioessays》 被引量: 61发表...
Human pluripotent stem cells (hPSCs) are adhesion-dependent cells that require cultivation in colonies to maintain growth and pluripotency. Robust differentiation protocols necessitate single cell cultures that are achieved by use of ROCK (Rho kinase) inhibitors. ROCK inhibition enables maintenance of stem...