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Human Induced Pluripotent Stem Cell GenerationIsao AsakaShinya YamanakaHuman Stem Cell Manual (Second Edition)
Human induced pluripotent stem cells (hiPSC)‐derived endothelial cells: new opportunity for corneal bioengineeringPurpose hiPSCs can self-renew indefinitely, while maintaining the capacity to differentiate into somatic cells. As such, they represent an essentially inexhaustible source of committed corneal ...
Human induced pluripotent stem cells (hiPSCs) can be endlessly produced and efficiently differentiated into cardiomyocytes (hiPSC-CMs) enabling development of human-based cell models for the research of cardiac diseases and therapies6. However, hiPSC-CMs are developmentally immature and structurally, funct...
Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development | Physiological Reviews 以下为全文翻译(水平有限,仅供参考): 摘要: 体细胞核移植的发现证明,体细胞可以携带与受精卵相同的遗传密码,激活该密码的部分足以将细胞重新编程到早期发育状态。近半个世纪后,诱导多能干细胞 (iPSC...
ACTA Activin A, AFE anterior foregut endoderm, DE definitive endoderm, hiPSC human induced pluripotent stem cells, NG noggin, SB SB-431542, VBP vocal fold basal progenitors. Source data provided as a Source Data file Full size image To qualitatively assess hiPSC-derived VBP, we conducted RNA ...
Human induced pluripotent stem (iPS) cells and human embryonic stem cells are cells that have the ability to differentiate into a variety of cell types. Embryonic stem cells are derived from human embryos; however, by contrast, human iPS cells can be obtained from somatic cells that have underg...
Chemical reprogramming of human somatic cells to pluripotent stem cells | Nature 以下为全文翻译(水平有限,仅供参考): 摘要 细胞重编程可以控制细胞的特性以产生所需的细胞类型1-3。使用细胞固有成分,包括卵子细胞质和转录因子,可以强制体细胞重编程为多能干细胞4-7。相比之下,暴露于小分子的化学刺激提供了另一...
The in vitro production of mature human red blood cells (RBCs) from induced pluripotent stem cells (iPSCs) has been the focus of research to meet the high demand for blood transfusions. However, limitations like high costs and technological requirements restrict the use of RBCs produced by iPSC...
Centrosomal abnormalities in human embryonic stem cells. Z Holubcová,P Dvořák,A Hampl - 《Biometrics》 被引量: 15发表: 2007年 Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders While induced pluripotent stem cells (iPSCs) have replaced the ethically ques...