We provide cells equivalent to embryonic stem cells in adults. Surface antigen CD44CD45Isolated pluripotent mammalian stem cells characterized by HLA class I and II negativeA method for treating cancer in mammals using said cellsAndA method for isolating a pluripotent adult stem cell (MASC);(a) ...
Development of treatments for vocal dysphonia has been inhibited by lack of human vocal fold (VF) mucosa models because of difficulty in procuring VF epithelial cells, epithelial cells’ limited proliferative capacity and absence of cell lines. Here we r
human pluripotent stem cellsCardiac muscle expresses predominantly larger N2BA titin isoforms at embryonic and prenatal stages of development, and these are mostly replaced with a smaller N2B isoform in adults. We have previously discovered a mutation in rats that dramatically alters titin splicing (...
In this review, we will describe the use and manipulation of human induced pluripotent stem cells (hiPSCs) in dissecting the interaction between ApoE and AD. First, we will provide an overview of the proposed roles that ApoE plays in modulating pathophysiology of AD. Next, we will summarize ...
Expression of pluripotency factors and in vitro differentiation into cell types of the three germ layers was unaffected in the analyzed clone PMM2-iPSC-C3 compared with nondiseased human pluripotent stem cells (hPSCs), revealing no broader influence of the PMM2 mutation on pluripotency in cell ...
Stem cells This article is cited by Definitive Endodermal Cells Supply an in vitro Source of Mesenchymal Stem/Stromal Cells Yumeng Zhang Ye Yi Guokai Chen Communications Biology(2023) Reprogramming of fibroblasts into expandable cardiovascular progenitor cells via small molecules in xeno-free conditions...
We examined the efficacy of tympanic (T(ty)) and exhaled breath (T(X)) temperatures as indices of rectal temperature (T(re)) by applying heat (condition A) and cold (condition B) in a dynamic A-B-A-B sequence. Fifteen healthy adults (8 men; 7 women; 24.9 +/- 4.6 years) volunte...
Human pluripotent stem cells (hPSCs), including human embryonic stem cells (hESCs) and human-induced pluripotent stem cells (hiPSCs), have unique features, including self-renewal and pluripotency. Recent advancements in differentiation techniques using hPSCs have led to the development of organoid techno...
human pluripotent stem cell human iPSC cerebral organoid microglia synaptic pruning Zika virus Introduction Microglia, as the innate immune cells of the central nervous system (CNS), play critical roles in neurodevelopment and tissue homeostasis. During brain development, microglia phagocytize apoptotic ce...
Human induced pluripotent stem cells (iPSCs) have been generated with varied efficiencies from multiple tissues. Yet, acquiring donor cells is, in most instances, an invasive procedure that requires laborious isolation. Here we present a detailed protoco