百度试题 题目Embryonic stem cells (ES cells) are pluripotent stem cells derived from the outer cell mass of a blastocyst, an early-stage pre-implantation embryo.相关知识点: 试题来源: 解析 错 反馈 收藏
一些研究已经报道了良好的OSKM化学计量学在多能性方面具有选择性优势。Jaenisch实验室制备了“次级”体细胞( “secondary” somatic cells),即携带强力霉素(doxycycline)诱导的OSKM表达的细胞,显示出比正常体细胞更高的重编程效率(368)。增强OCT3/4表达但降低SOX2表达也能提高重编程效率(265,380),调节KLF4表达也能提高...
Embryonic stem cells are pluripotent cells isolated from the inner cell mass of a blastocyst, the early mammalian embryo that implants into the uterus. Embryonic stem cells self-renew by dividing and can differentiate into any specialised cell of the body, but not extra-embryonic tissues such as...
多能干细胞(Pluripotent Stem Cells) 简介 如前所述,人多能干细胞 (PSC) 的特点是能够无限制自我更新,当遇到合适的环境时,可以分化成人体的几乎任意细胞类型。常用于研究的两种 PSC 是胚胎干细胞 (ESC) 和诱导 PSC(iPSC) ( 图2)。人 ESC 分离自发育胚胎的胚泡期内细胞群1。 iPSC 与 ESC 类似或相当,但通...
多功能干细胞cellsMesh多能干细胞词汇词表日本京都大学c-Myc译文:诱导多能干细胞:2006年日本京都大学Shinya Yamanaka在世界著名学术杂志《细胞》上率先报道了诱导多能干细胞的研究.他们把Oct3/4,Sox2,c-Myc和Klf4这四种转录因子基因克隆入病毒载体中国组织工程研究...
they will becomeintegratedinto the embryo and produce cells that differentiate into most or all of the tissue types that subsequently develop. This ability to repopulate mouse embryos is the key defining feature of embryonic stem cells, and because of it they are considered to bepluripotent—that ...
Several mouse pluripotent stem cell types have been established either from mouse blastocysts and epiblasts. Among these, embryonic stem cells (ESCs) are considered to represent a “naïve”, epiblast stem cells (EpiSCs) a “primed” pluripotent state. Although EpiSCs form derivatives of all thr...
These cells, termed “induced pluripotent stem cells” or iPS cells, appear to have almost all the versatility of true embryonic stem cells, but can be obtained far more easily, in far greater numbers, and without the main ethnical challenges that have confronted the embryonic stem cell field....
13.2.2.2Induced pluripotent stem cells The establishment of inducedpluripotent stem cells(iPSCs) has been considered a groundbreaking discovery in stemcell biologyand medicine (Huang, 2010). With this approach, almost any cell type can be reprogrammed into pluripotent stem cells by delivering four fact...
cells can yield therapies whereas other research cannot, such as adult stem cells and induced pluripotent stem cells (iPSC). The clinical trials like Geron’s on spinal cord injury and Advanced Cell Technology (ACT)’s on blindness caused by macular degeneration were promising during preliminary ...