一些研究已经报道了良好的OSKM化学计量学在多能性方面具有选择性优势。Jaenisch实验室制备了“次级”体细胞( “secondary” somatic cells),即携带强力霉素(doxycycline)诱导的OSKM表达的细胞,显示出比正常体细胞更高的重编程效率(368)。增强OCT3/4表达但降低SOX2表达也能提高重编程效率(265,380),调节KLF4表达也能提高...
Here we provide a detailed method to differentiate homeostatic microglia from human pluripotent cells. Additionally, due to the innate sensitivity of these immune cells, we have provided detailed notes for best practices of handling cultured microglia.McQuade, Amanda...
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Human induced pluripotent stem cells (hiPSC)‐derived endothelial cells: new opportunity for corneal bioengineeringPurpose hiPSCs can self-renew indefinitely, while maintaining the capacity to differentiate into somatic cells. As such, they represent an essentially inexhaustible source of committed corneal ...
ACTA Activin A, AFE anterior foregut endoderm, DE definitive endoderm, hiPSC human induced pluripotent stem cells, NG noggin, SB SB-431542, VBP vocal fold basal progenitors. Source data provided as a Source Data file Full size image To qualitatively assess hiPSC-derived VBP, we conducted RNA ...
Human induced pluripotent stem cells (hiPSCs) can be endlessly produced and efficiently differentiated into cardiomyocytes (hiPSC-CMs) enabling development of human-based cell models for the research of cardiac diseases and therapies6. However, hiPSC-CMs are developmentally immature and structurally, funct...
英文名称:iPS Human Induced Pluripotent Stem Cells 英文同义词:iPS Human Induced Pluripotent Stem Cells CAS号: 分子式: 分子量:0 EINECS号: 信息错误报告 您的Email: 按国家浏览iPS Human Induced Pluripotent Stem Cells国外供应商中国供应商 iPS Human Induced Pluripotent Stem Cells推荐供应商 ...
Human induced pluripotent stem cells (iPS cell) differentiate into trophoblast lineageHuman induced pluripotent stem cells (iPS cell) differentiate into trophoblast lineagedoi:10.1016/j.placenta.2016.08.075IsakaNatlKeiichiNatlKojimaNatlJunyaNatlKujiNatl...
Human induced pluripotent stem cell (iPSC)-derived macrophages (IPSDM), as an unlimited source of subject genotype-specific cells, will undoubtedly play an important role in advancing our understanding of the role of macrophages in human diseases. In this review, we summarize current literature in...
Mesenchymal stem cells(MSCs) derived from human induced pluripotent stem cells(hiPSCs) provide a novel source for generating adipocytes, thus opening new avenues for fundamental research and clinical medicine. We present the adipogenic potential of hiPSCs and the various methods to derive hiPSC-MSCs. ...