including tumor necrosis factor (TNF)-α, interleukin (IL)−1, IL-6, and interferon gamma (IFN-γ). To further explore the CRS-related cytokine functions, we summarized 12 cytokines and divided them into three groups: antitumor effectors (granzyme B (GZMB), IFN-γ, macrophage inflammatory...
Hu, D.-N. et al. Interleukin-1β increases baseline expression and secretion of interleukin-6 by human uveal melanocytes in vitro via the p38 MAPK/NF-κB pathway.Investigative Opthalmology Vis. Sci.52, 3767 (2011). ArticleCASGoogle Scholar Sato, T., Takeuchi, M., Karasawa, Y., Enoki, ...
MP1 MEK partner 1 JIP JNK-interacting protein TNF tumor necrosis factor IL interleukin MLK mixed-lineage kinase RTK receptor tyrosine kinase ASK1 apoptosis signal-regulating kinase 1 ROS reactive oxygen species LPS lipopolysaccharide ER endoplasmic reticulum AD Alzheimer's disease Aβ amyloid-β APP ...
Interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and cardiotrophin-1 (CT-1) mRNA expression and secretion were measured using quantitative real-time RT-PCR and enzyme-linked immunosorbent assay. IL-1α (0.001-10 ng/ml, 0-6 h) stimulated IL-1β, ...
Interleukin-12 and the regulation of innate resistance and adaptive immunity Nat Rev Immunol, 3 (2003), pp. 133-146 CrossrefView in ScopusGoogle Scholar Ueno et al., 2007 H. Ueno, E. Klechevsky, R. Morita, et al. Dendritic cell subsets in health and disease Immunol Rev, 219 (2007),...
(DON) on HuR translocation and its involvement in the regulation of the pro-inflammatory interleukin-8 (IL-8) mR. ELAVL1 is an RNA binding protein involved in translation control, which might have a regulatory role in prostate cancer progress. ELAVL1 is an RNA binding protein involved in ...
Because both the brain natriuretic peptide (BNP) gene and the cytokine interleukin-1beta (IL-1beta) are induced in the infarcted myocardium, localized production of IL-1beta may regulate the BNP gene. We tested whether (1) IL-1beta regulates the human BNP promoter, (2) cis elements in th...
[20]Masckauchan TN, Shawber CJ, Funahashi Y, Li CM, Kitajewski J (2005) Wnt/beta-catenin signaling induces proliferation, survival and interleukin-8 in human endothelial cells. Angiogenesis 8: 43–51. doi: 10.1007/s10456-005-5612-9 ...
Interleukin (IL)-1 was first cloned in the 1980s, and rapidly emerged as a key player in the regulation of inflammatory processes. The term IL-1 refers to two cytokines, IL-1α and IL-1β, which are encoded by two separate genes. The effects of IL-1 are tightly controlled by several...
fostering an environment that promotes tumor growth by enhancing interleukin (IL)-4-mediated reprogramming and suppressing IFNγ-induced gene expression. The deletion of ABC transporters, responsible for cholesterol efflux, reversed the tumor-promoting functions of TAMs, leading to reduced tumor progression...