Interleukin 2 (IL-2) is a pleiotropic cytokine produced primarily by T lymphocytes. The mature mouse IL-2 is a 149 amino acid (aa) residue glycoprotein. Human IL-2 is synthesized as a 153 amino acid precursor that contains a 20 amino acid signal sequence plus a 133 amino acid mature reg...
针对Interleukin 2, Human (IL-2), BioAssay ELISpot Kit该产品的特点优势,欢迎查阅官网提供的产品说明书。保存建议 建议收到Interleukin 2, Human (IL-2), BioAssay ELISpot Kit产品后将其置于-20°C保存。其他 Usbiological公司是美国著名的抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫...
A cDNA coding for human interleukin-2 (IL-2) has been cloned from a cDNA library prepared from partially purified IL-2 mRNA. The DNA sequence codes for a polypeptide which consists of 153 amino acids including a putative signal sequence. A biologically active polypeptide, characteristic of ...
Interleukin 2 (IL-2), also known as T cell growth factor (TCGF), is a 15-18 kDa variably glycosylated alpha -helical polypeptide that is a member of the Common gamma Chain ( gamma c) cytokine family (1-4). It exists as a monomer and has a notably short half-life (< 30 minutes...
The occurrence of many autoimmune diseases takes root on the disrupted balance among Treg cells, Teff cells, etc. Low-dose interleukin-2 (IL-2) cytokine demonstrates promising clinical efficacy in the expansion of Treg cells and the treatment of autoimmu
inflammatory responses by modulating chromatin at cis-regulatory regions of inflammatory genes (Chen and Ivashkiv, 2010), reprogramming metabolism (Cheng et al., 2016, Su et al., 2015), modulating mRNA translation (Su et al., 2015), and antagonizing interleukin (IL)-4 (Piccolo et al., ...
B-cell-stimulatory factor 2 (β2 interferon) functions as a second signal for interleukin 2 production by mature murine T cells Proc Natl Acad Sci USA, 84 (1987), pp. 7629-7633 Google Scholar 18 MX Du, WD Sotero-Esteva, MW Taylor Analysis of transcription factors regulating induction of ...
Interleukin 2 (IL-2), also known as T cell growth factor (TCGF), is a 15-18 kDa variably glycosylated alpha-helical polypeptide that is a member of the Common gamma Chain ( gammac) cytokine family (1-4). It exists as a monomer and has a notably short half-life (< 30 minutes) (...
D. Cytoplasmic domains of the interleukin-2 receptor beta and gamma chains mediate the signal for T cell proliferation. Nature 369, 333–336 (1994). Article CAS PubMed Google Scholar Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M. & Toda, M. Immunologic self-tolerance maintained by...
Much of the genetic variation implicated in type 1 diabetes is associated with major histocompatibility antigens, interleukin-2 signalling, T cell receptor signalling and interferon signalling39,40,41. The SNP catalogue contained 76 SNPs linked to type 1 diabetes, of which 66 occurred in noncoding...