Dendritic cells (DCs) are currently considered to be of utmost importance for orchestrating appropriate immune responses in vivo, and play critical roles in maintaining the distinction between self and non-self. They are distributed throughout most tissues of the body, where they are well positioned...
Dendritic Cells in Human Cancerdoi:10.1002/9783527619696.ch51human cancerimmune systemtissuesdifferentiationmigrationCasey A. CarlosOlivera J. FinnJohn Wiley & Sons, Ltd
Dendritic Cells in Human Cancer AIM: To analyze the prognostic significance of CD83, CD1a, and Ki-67 expression in colorectal carcinoma. METHODS: The expression of CD83, CD1a, and Ki-67 i... CA Carlos,OJ Finn - Wiley‐VCH Verlag GmbH 被引量: 0发表: 2008年 888: Activation and homing...
K. et al. Dendritic cells in cancer immunology and immunotherapy. Nat. Rev. Immunol. 20, 7–24 (2020). Article CAS PubMed Google Scholar Diebold, S. S., Kaisho, T., Hemmi, H., Akira, S. & Sousa, C. R. E. Innate antiviral responses by means of TLR7-mediated recognition of ...
Plasmacytoid dendritic cells (pDCs) highly populate lung tumor masses and are strictly correlated to bad prognosis, yet their role in lung cancer is controversial. To understand their role in lung cancer, we isolated pDCs from human samples of lung obtained from non-small cell lung cancer ...
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In cancer, clinical studies have reported a link between tetraspanin expression levels and prognosis and/or metastasis. Indeed a high level of the tetraspanins CD9 and CD82/KAI-1 on tumor cells is associated with a favorable prognosis in breast, lung, colon, prostate, and pancreas cancers. Add...
Indeed, MSCs are strong contributors to tumor growth and progression in different cancer types [15–17], although anti-tumor activities have also been reported underscoring their pleiotropic properties [18, 19]. A unique aspect of MSCs is that they strongly respond to inflammatory signals causing ...
The role of type 1 conventional dendritic cells in cancer immunity. Trends Cancer 4, 784–792 (2018). Article PubMed PubMed Central CAS Google Scholar Alcántara-Hernández, M. et al. High-dimensional phenotypic mapping of human dendritic cells reveals interindividual variation and tissue ...
In atherosclerosis, some regulatory T (Treg) cells become exTreg cells. We crossed inducible Treg and exTreg cell lineage-tracker mice (FoxP3eGFP−Cre-ERT2ROSA26CAG-fl-stop-fl-tdTomato) to atherosclerosis-prone Apoe−/− mice, sorted Treg cells and exTreg cells and determined their tran...