A cross-validated average prediction accuracy of 93% was reached for distinction between cytoplasmic and non-cytoplasmic proteins, based on the analysis of protein amino-acid composition. Principal component analysis and self-organizing maps were used to create graphical representations of amino-acid ...
To determine if Sc spores are dispersed by Bs, 3 μl of Bs cells are inoculated onto the plate and 3 μl of Sc spore stocks are either added on the Bs inoculation site or to a separate inoculation site. The plates are incubated at 30 °C for 5 days and imaged on a light ...
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and interacting with diffusion molecules55based on cell density in the surrounding environment38.S. mutansutilize this system to communicate with each other as a group rather than as separate individuals. The main mechanism for signal feedback is via the two-component signal transduction systems (TCS...
cytoplasmic membrane (Figure 2). The Z ring is anchored by FtsZ-binding proteins and defines the division plane between the two daughter cells. Additional proteins required for cell division are added to the Z ring to form a structure called the divisome. The divisome activates to produce a ...
Cytosol is the fluid that’s found inside living cells. More specifically, it’s the water-based fluid in which organelles, proteins and other structures of the cell live. Also known as the cytoplasmic matrix, it constitutes most of the intracellular flu
Localization can be used to bring proteins together or to separate them. For example, we found an extremely rare mutation in the gene that codes for a secreted protein, the luteinising hormone beta (LHB), in a patient. To prove that the wildtype (WT) and mutant proteins were ...
inspection, we discovered that the MX protein orchestrates the assembly of nucleoporins into biomolecular condensates, membrane-less droplets inside a cell that act like a separate compartment. Viruses mistake these condensates for the actual cell door to the cell nucleus and get trapped or punctured...
Adherens junction provides strong mechanical attachment between neighbouring cells through the linkage of their cytoplasmic face to the actin cytoskeleton. BAR-domain protein Highly conserved protein dimerization domains that occur in many proteins involved in membrane dynamics and act as connecting links ...
An essential family of PRRs is the inflammasome sensor family, cytosolic proteins that upon activation trigger inflammatory signaling and cell death. Inflammasomes are multiprotein complexes that consist of a sensor, the adaptor protein ASC, and caspase-1; these components assemble following sensor activ...