For example, nuclei were not segmented in the Cellpose dataset if they were missing a cytoplasm or membrane label (Fig. 1a(i)), but they were always labeled in the TissueNet dataset (Fig. 1b(i),(iii)). Processes that were diffuse were not segmented in the Cellpose dataset (Fig. 1a(...
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Cytokinesis in animal cells is more complex than in plant cells. A contractile ring, underneath the original cell's membrane, begins to form and contracts, which creates the cleavage furrow. The furrow grows deeper between the two cells until they pinch off and separate from one another, result...
Potassium efflux has been proposed as a general upstream requirement for activating the NLRP3 inflammasome. Many NLRP3 activators, including the potassium ionophores nigericin and gramicidin and pore-forming toxins that permeabilize the plasma membrane to potassium, enable potassium efflux [10,11,12]. ...
However, cells must control the natural tendency of proteins and nucleic acids to phase separate to build functional condensates at the correct time and location. The cellular mechanisms that regulate phase separation thus are a critical part of understanding how cells use biomolecular condensation to ...
How do cell differentiation and cell division work together? How do the nucleus and endoplasmic reticulum work together? What technique is used to separate the different cell parts? How do plant cells divide? Why are all different parts of the cell necessary?
Figure 2. FtsZ proteins assemble to form a Z ring that is anchored to the plasma membrane. The Z ring pinches the cell envelope to separate the cytoplasm of the new cells. Think about It What is the name of the protein that assembles into a Z ring to initiate cytokinesis and cell divi...
Suggest why hydrolytic enzymes within cells need to be inside a vesicle Because vesicles have a membrane which keeps the enzymes separate from the cytoplasm. If there was no vesicle, the enzymes would hydrolyse all other organelles in the cytoplasm. ...
Among the physicochemical cues in the cellular microenvironment that orchestrate cell processes, the different levels of curvature in the extracellular matrix and intrinsic to the tissues play a pivotal role in the spatiotemporal control of key cellular
Having both NLS/NES will result in the protein being shuttled between cytoplasm and the nucleus. Likewise, mitochondrial targeting signals (MTS) have been used to attach proteins to the mitochondria's outer membrane for many different reasons, e.g., to label mitochondria by use of ...