Several neurodegenerative disorders are characterized by the presence of cytoplasmic proteinaceous inclusions termed Lewy bodies (LBs), which are enriched in misfolded and aggregated forms of the presynaptic protein alpha-synuclein (α-syn) (Goedert et al., 2017). These diseases include Parkinson's dis...
Oxidative injury, reflected by the cytoplasmic accu- mulation of oxidized lipids in white matter lesions and the cortex was low in comparison to that seen in acute MS cases with Pattern III pathology or in the lesions of patients with progressive MS. [14, 21] However, in the lesions ...
(A) Bone marrow aspirate of ALL cells exhibiting a high nuclear to cytoplasmic ratio, finely dispersed chromatin, indistinct nucleoli, and blue-gray cytoplasm. (B) Bone marrow biopsy showing effacement of the marrow architecture by a monotonous population of ALL lymphoblasts. (C) Representative nor...