Factor V Leiden mutationPubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites....
Resistance to activated protein C (APC) is a common inherited risk factor for venous thrombosis, which is associated with a mutation in coagulation factor V (factor V Leiden). We investigated the risk of venous thrombosis in individuals homozygous for this abnormality. We determined the factor V...
High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance) Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver dise...
BACKGROUND: Factor V Leiden mutation represents the most common genetic risk factor of venous thrombosis in Caucasian population. A common mutation in prothrombin gene, which is due to G-->A transition at position 20210, is also associated with elevated prothrombin concentration and thrombosis. Both...
Extensive hepatic infarction caused by thrombosis of right portal vein branches and arterial vasospasm in HELLP syndrome associated with homozygous factor ... (1998) Extensive hepatic infarction caused by thrombosis of right portal vein branches and arterial vasospasm in HELLP syndrome associated with ...
Kyung A. Kang
Risk of venous thromboembolism during pre- gnancy in homozygous carriers of the factor V Leiden muta- tion: are there any predictive factors? J Throm Haemost 2004; 2: 359-60.The Procare Group. Risk of venous thromboembolism during pregnancy in homozygous carriers of the factor V Leiden ...
The patient was also heterozygous for the factor V Leiden mutation. The AT gene mutation was present at the heterozygous state in both parents (who were first cousins) and in the mother's elder sister. Heterozygotes had borderline AT levels and only one of 3 heterozygous adult relatives ...
Whether the factor V Leiden mutation increases the risk of recurrent venous thromboembolism (VTE) remains controversial, and homozygous carriers have not been extensively evaluated. In the present cohort study, we have assessed the incidence of recurrent VTE in a subset of non-treated patients previou...
A Case Control Study on the Contribution of Factor V-Leiden, Prothrombin G20210A, and MTHFR C677T Mutations to the Genetic Susceptibility of Deep Venous Th... BACKGROUND: Insofar as the inherited prothrombotic single nucleotide polymorphisms (SNPs) factor V G1691A (FV-Leiden), prothrombin (PRT...