Heterozygous Factor V Leiden deficiency with hepatic thrombosis in a twin pregnancy: a near missHepatic VeinsPregnancy, MultipleAdultFactor VFactor V DeficiencyFemaleHeterozygoteHumanPregnancyPregnancy Complications, CardiovascularDepartment of Obstetrics and Gynaecology, Hemel Hempstead General Hospital, Hemel ...
Stroke in a Child with Heterozygous Factor V Leiden Mutation [Heterozigot Faktör V Leiden Mutasyonu olan İnmeli Bir Çocuk]Although thrombosis is seldom seen in children, reports of young patients with thrombosis are becoming more frequent with time. Activated protein C resistance, caused ...
We report here the evolution of the thrombin generation profile while taking combined oral contraceptives and after their discontinuation in a woman with heterozygous factor V Leiden mutation. The proband exhibited a distinctly prothrombotic thrombin generation profile including markedly decreased thrombomodulin...
Presents a letter to the editor regarding a Budd-Chiari syndrome with underlying homozygous factor V Leiden and heterozygous methylenetetrahydrofolate reductase mutations.doi:10.1007/s00535-005-1664-2Kassem A. BaradaCecilio R. AzarZaher K. Otrock...
Idiopathic Budd–Chiari syndrome in a patient with homozygous Factor V Leiden and heterozygous Factor II G20210A mutations Idiopathic Budd-Chiari syndrome in a patient with homozygous factor Leiden and heterozygous Factor G20210A mutation on the prothrombin gene. de Stefano V,... VD Stefano,P ...
Summary Background The high allelic frequency of the prothrombotic Leiden polymorphism in human blood coagulation factor V (FV) has been speculated to reflect positive selection during evolution. Heterozygous Leiden carriers enrolled in the placebo arm of the PROWESS sepsis trial and heterozygous Leiden ...
Severe Protein S Deficiency Associated with Heterozygous Factor V Leiden Mutation in a Child with Purpura Fulminans Homozygous or compound heterozygous protein S (PS) deficiency is very rare in the population; only 8 patients from 6 different families have been reported... Y Dogan,D Aygun,Y Yilm...
Seven infants were factor V Leiden heterozygous and another one homozygous. Methylenetetrahydrofolate reductase genotype was found in 5 infants. Five cases were found to be double heterozygous for those two mutations, and another one double heterozygous for FVL and factor II. The results of this ...
Activated protein C resistance is the most common hereditary coagulation abnormality and is caused by the factor V Leiden mutation. A newborn who developed seizures within hours after delivery and was found to have a bihemispheric stroke is described. This patient, determined to be heterozygous for...
all FECD patients examined for methylation pattern were genotyped forF5rs6025 andF2rs1799963. Only one FECD patient was found to be heterozygous carrier of theF2rs1799963G > A variant, and it was the same individual (FECD case 15) that was excluded from the analysis due to poor quali...