Heterozygous factor V Leiden mutation manifesting with combined central retinal vein occlusion, cilioretinal artery occlusion, branch retinal artery occlusion, and anterior ischaemic optic neuropathy: a case reportCentral retinal vein occlusionCilioretinal artery occlusion...
Homozygous carriers of factor V Leiden have an approximately 80-fold increased risk of venous thrombosis. Also double heterozygous carriers of both the fac... I Martinelli,C Legnani,P Bucciarelli,... - 《Thrombosis & Haemostasis》 被引量: 373发表: 2001年 The clinical outcome after inferior ven...
Double-homozygosity for factor V Leiden and the prothrombin gene G20210A variant in a young patient with idiopathic venous thrombosis. Blood. 1999; 94 :... JR Mainardi,PM Pelsma,H Koning,... - 《Blood》 被引量: 14发表: 1999年 Anticoagulation Therapy in a Patient With Heterozygous Factor ...
Factor V Leiden (FVL)-carrying relatives of selected patients with venous thromboembolism (VTE) have much higher venous thrombotic risks than FVL-carrying ... Ruud,Lensen,Rogier,... - 《Br J Haematol》 被引量: 76发表: 2001年 Severe Protein S Deficiency Associated with Heterozygous Factor V Le...
The factor V Leiden mutation in 12 children with thrombosis and in 20 controls was investigated. Five heterozygous individuals and 1 homozygous individual among the cases with thrombosis and 1 heterozygous individual among controls were found. Central nervous system thromboses were increased in children ...
Presents a letter to the editor regarding a Budd-Chiari syndrome with underlying homozygous factor V Leiden and heterozygous methylenetetrahydrofolate reductase mutations.doi:10.1007/s00535-005-1664-2Kassem A. BaradaCecilio R. AzarZaher K. Otrock...
Summary Background The high allelic frequency of the prothrombotic Leiden polymorphism in human blood coagulation factor V (FV) has been speculated to reflect positive selection during evolution. Heterozygous Leiden carriers enrolled in the placebo arm of the PROWESS sepsis trial and heterozygous Leiden ...
It is well documented that factor V Leiden mutation (FVL) is a common hypercoagulable risk factor in the Caucasian population. Patients with homozygous FVL mutation have an increased risk for venous thromboembolism. However, there have been few cases of heterozygous FVL mutation associated with ...
Seven infants were factor V Leiden heterozygous and another one homozygous. Methylenetetrahydrofolate reductase genotype was found in 5 infants. Five cases were found to be double heterozygous for those two mutations, and another one double heterozygous for FVL and factor II. The results of this ...
Stroke in a Child with Heterozygous Factor V Leiden Mutation [Heterozigot Faktör V Leiden Mutasyonu olan İnmeli Bir Çocuk]Although thrombosis is seldom seen in children, reports of young patients with thrombosis are becoming more frequent with time. Activated protein C resistance, caused ...