The rate of early and late fetal loss was assessed and was compared among factor V Leiden homozygous, factor V Leiden heterozygous, and noncarriers, and the impact of concomitant thrombophilic abnormalities was examined. Results show that risk of fetal loss is higher in women who were homozygous...
Resistance to activated protein C (APC) is a common inherited risk factor for venous thrombosis, which is associated with a mutation in coagulation factor V (factor V Leiden). We investigated the risk of venous thrombosis in individuals homozygous for this abnormality. We determined the factor V...
Testing with allele-specific polymerase chain reaction for FII mutation and factor V Leiden showed a double homozygous pattern for both factor V Leiden and c.*97G > A FII mutation (Fig. 2). Since this genetic combination is unusual, next-generation DNA sequencing of the factor V and factor...
OBJECTIVE: To assess the rate of early (first trimester) and late (second and third trimester) fetal loss in women who are factor V Leiden homozygous. METHODS: Between December 1995 and February 2007, consecutive, unrelated white women who were factor V Leiden homozygous and who had been pregn...
Successful liver transplantation in a patient with Budd-Chiari syndrome caused by homozygous factor V Leiden. JS, Maley WR, Merritt WT, Klein AS: Successful liver transplantation in a patient with Budd-Chiari syndrome caused by homozygous factor V Leiden. Liver... HP Tan,JS Markowitz,WR Maley,...
Kyung A. Kang
Standen GR, Morse C et al.DVT following oral contraceptive therapy in association with homozygous factor V Leiden. Aslam S. Clinical and Laboratory Haematology . 1995Aslam S.Standen GR, Morse C et al.DVT following oral contraceptive therapy in association with homozygous factor V Leiden.Clinical ...
Factor V Leiden homozygous genotype and pregnancy outcomes. Obstet Gynecol 2009;114: 1249 –1253. 78. Prandoni P, Lensing AW, Cogo A, et al. The long-term clinical course of acute deep venous thrombosis. Ann Intern Med 1996;125:1–7. 79. Christiansen SC, Cannegieter SC, Koster T, ...
Presents a letter to the editor regarding a Budd-Chiari syndrome with underlying homozygous factor V Leiden and heterozygous methylenetetrahydrofolate reductase mutations.doi:10.1007/s00535-005-1664-2Kassem A. BaradaCecilio R. AzarZaher K. Otrock...
Adjustment for these thrombotic risk factors did not affect the risk of recurrence among heterozygous carriers of FV Leiden. Our analysis was restricted to heterozygous carriers of FV Leiden. Among homozygous carriers of the mutation, the risk of recurrence still remains unknown. In ...