Homozygous factor V Leiden mutationThoracic angioscanPulmonary embolism is a frequent and potentially serious pathology.The etiological assessment of pulmonary embolism is not carried out in a systematic way which makes the management not optimal with the possibility of repeated pulmonary embolism.Long-...
Compound heterozygosity for factor V Leiden and prothrombin G20210A mutations in a child with Budd-Chiari syndrome Colak Y; Karasu Z; Oruc N;.Hyperhomocysteinaemia and factor V Leiden mutation are associated with Budd-Chiari syndrome.Eur J Gastroenterol H epatol... T Sipahi,F Duru,NY Akar...
Resistance to activated protein C (APC) is a common inherited risk factor for venous thrombosis, which is associated with a mutation in coagulation factor V (factor V Leiden). We investigated the risk of venous thrombosis in individuals homozygous for this abnormality. We determined the factor V...
High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance) Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver dise...
Laboratory investigations revealed severe homozygous protein C deficiency associated with homozygous factor V Leiden, although her pregnancy and perinatal periods were otherwise uneventful, with negative family history of thrombotic or bleeding disorders. Patient stabilization was established by supportive ...
Kyung A. Kang
Regulation of thrombin formation by activated protein C: effect of the factor V Leiden mutation. Activated Protein C (APC) resistance, one of the most common genetic risk factors for venous thrombosis, is caused by a single base mutation (G1691-->A) in the factor V (FV) gene resulting in...
factor V Leiden or heterozygous G20210A mutation in the prothrombin gene is associated with a pregnancy-associated thrombotic risk of approximately 1 in 400... Rainer,B,Zotz,... - 《Best Practice & Research Clinical Haematology》 被引量: 76发表: 2003年 Two cases of refractory thrombotic thromb...
Is recurrent venous thromboembolism more frequent in homozygous patients for the factor V Leiden mutation than in heterozygous patients? 来自 Semantic Scholar 喜欢 0 阅读量: 25 作者: None 摘要: Whether the factor V Leiden mutation increases the risk of recurrent venous thromboembolism (VTE) ...
Thromboembolism is a multicausal disease in which both acquired and genetic risk factors play a role and their interaction is common. Inherited thrombophilia is now demonstrated to be a multigenic disease; the most common genetic risk factors are the factor V Leiden and the prothrombin mutations. ...