Homozygous factor V Leiden mutationThoracic angioscanPulmonary embolism is a frequent and potentially serious pathology.The etiological assessment of pulmonary embolism is not carried out in a systematic way which makes the management not optimal with the possibility of repeated pulmonary embolism.Long-...
The most common forms of familial thrombophilia are factor V Leiden (FVL) and prothrombin mutation (PTM). Homozygous FVL and PTM have long been feared conditions thought to cause high rates of morbidity and mortality. To analyse clinical features in patients with homozygous FVL and PTM, as well...
Primary Budd–Chiari syndrome in a 3-year-old boy with homozygous factor V Leiden G1691A mutation Budd鈥揅hiari syndrome (BCS) is an uncommon disorder characterized by obstruction of hepatic venous outflow. The primary BCS is a rare disease with an inci... A Boskovic,I Kitic,I Stankovic…...
OBJECTIVE: To assess the rate of early (first trimester) and late (second and third trimester) fetal loss in women who are factor V Leiden homozygous. METHODS: Between December 1995 and February 2007, consecutive, unrelated white women who were factor V Leiden homozygous and who had been pregn...
Funnel plots for all five meta-analyses: A—factor V Leiden; B—prothrombin; C—protein C; D—protein S; E—antithrombin. Table S1. Studies included in the meta-analysis. Author Contributions Conceptualization, M.T.-M.; data curation, M.T.-M.; formal analysis, M.L.; software, M.L...
Resistance to activated protein C (APC) is a common inherited risk factor for venous thrombosis, which is associated with a mutation in coagulation factor V (factor V Leiden). We investigated the risk of venous thrombosis in individuals homozygous for this abnormality. We determined the factor V...
Severe Protein S Deficiency Associated with Heterozygous Factor V Leiden Mutation in a Child with Purpura Fulminans Homozygous or compound heterozygous protein S (PS) deficiency is very rare in the population; only 8 patients from 6 different families have been reported... Y Dogan,D Aygun,Y Yilm...
Kyung A. Kang
factor V LeidenBudd-Chiari syndromeComment on Br J Haematol. 1998 Sep;102(4):929-31.doi:10.1046/j.1365-2141.1999.01487.xGurjeewan GarewalReena DasYogesh ChawlaR K DhimanBlackwell Science LtdBritish Journal of HaematologyGarewal G,,Das R,Chawla Y.Budd-Chiari syndrome associated with homozygous ...
Rare homozygous FVL mutations present somewhat greater risks of VTE recurrence (OR: 2.65). The evidence for this increased risk is convincing, but the magnitude of excess risk is not as great as previously thought. The evidence is insufficient to draw conclusions about excess VTE recurrence risk ...