Homozygous factor V Leiden mutationThoracic angioscanPulmonary embolism is a frequent and potentially serious pathology.The etiological assessment of pulmonary embolism is not carried out in a systematic way which makes the management not optimal with the possibility of repeated pulmonary embolism.Long-...
Primary Budd–Chiari syndrome in a 3-year-old boy with homozygous factor V Leiden G1691A mutation Budd鈥揅hiari syndrome (BCS) is an uncommon disorder characterized by obstruction of hepatic venous outflow. The primary BCS is a rare disease with an inci... A Boskovic,I Kitic,I Stankovic…...
We found 36 patients homozygous for FVL. Patients homozygous for FVL were younger than controls at group level (56±18 vs. 63±17 展开 关键词: Homozygous factor V Leiden APC-resistance Thrombosis Venous thromboembolism Thrombophilia Heterozygous prothrombin mutation ...
Presence of factor V Leiden mutation is a known risk factor for thrombosis. It contributes for premature occlusion of vascular anastomosis. This report describes the intraoperative and postoperative anticoagulation management of a girl with homozygous factor V Leiden mutation and renal artery stenosis ...
Gurgey, "Clinical and laboratory evaluation of Turkish children with thrombosis for homozygous factor V G1691A mutation," Blood Coagulation and Fibrinolysis, vol. 15, no. 4, pp. 343–346, 2004. [20] I. Aschka, V. Aumann, F. Bergmann et al., "Prevalence of factor V leiden in ...
to distinguish heterozygotes from homozygotes. Patients on heparin therapy or with known lupus anticoagulant should proceed directly to molecular testing if the modified functional assay is not used. When relatives of individuals known to have factor V Leiden are tested, the DNA method is recommended...
By screening 174 healthy Lebanese subjects, 25 were shown to carry the FV-Leiden mutation, giving an allele frequency of 7.4% and an overall prevalence rate of 14.4%. Of the 25 FV-Leiden carriers, 24 were in the heterozygous state while one was in the homozygous states. No statistical ...
bIncludes heterozygous and homozygous individuals. utilization, also consistent with this hypothesis.22,23 However, an evolutionary survival benefit of Factor V Leiden has not been confirmed. DIAGNOSIS Clinical diagnosis No clinical features are specific for Factor V Leiden throm- bophilia. The ...
Kyung A. Kang
Aim. Lebanon exhibits one of the highest prevalences of factor V-Leiden (FVL) in the world (14.4%). The aim of this study is to evaluate the incidence of FVL mutation among Lebanese patients with lower extremity venous thrombosis. Material and Methods. F