Symptomatic combined homozygous factor XII deficiency and heterozygous factor V Leiden. J Thromb Thrombolysis 2000; 9: 271-5.Girolami A,Simioni P,Scaranol. Symptomatic combined,homozygous factor Ⅻ deficiency and heterozygous factor V Leiden[J].Thrombosis and Haemostasis,2000.271-275....
We found 36 patients homozygous for FVL. Patients homozygous for FVL were younger than controls at group level (56±18 vs. 63±17 展开 关键词: Homozygous factor V Leiden APC-resistance Thrombosis Venous thromboembolism Thrombophilia Heterozygous prothrombin mutation ...
Primary Budd–Chiari syndrome in a 3-year-old boy with homozygous factor V Leiden G1691A mutation Budd鈥揅hiari syndrome (BCS) is an uncommon disorder characterized by obstruction of hepatic venous outflow. The primary BCS is a rare disease with an inci... A Boskovic,I Kitic,I Stankovic…...
Presents a letter to the editor regarding a Budd-Chiari syndrome with underlying homozygous factor V Leiden and heterozygous methylenetetrahydrofolate reductase mutations.doi:10.1007/s00535-005-1664-2Kassem A. BaradaCecilio R. AzarZaher K. Otrock...
Clinical Va- lidity: The presence of a heterozygous FVL variant seems to be a weak risk factor for recurrence of VTE (odds ratio [OR]: 1.56). Rare homozygous FVL mutations present somewhat greater risks of VTE recurrence (OR: 2.65). The evidence for this increased risk is convincing, but...
Another variant, called the R2 allele (H1299R), appears to confer a modest additional increased thrombotic risk when present in the compound heterozygous state with factor V Lei- den.20 It has no clinically significant effect by itself, but in the homozygous state, it appears to increase APC...
Laboratory investigations revealed severe homozygous protein C deficiency associated with homozygous factor V Leiden, although her pregnancy and perinatal periods were otherwise uneventful, with negative family history of thrombotic or bleeding disorders. Patient stabilization was established by supportive ...
Among 471 patients, we found 85 (18%) who were heterozygous and seven (1.5%) who were homozygous for the defect, whereas the other 379 (80%) did not carry the factor V Leiden mutation. Among the 474 controls, 14 (2.9%) were heterozygous, and all other 460 were normal; there were ...
Kyung A. Kang
(2008) Management of a child with renal artery stenosis and homozygous factor V Leiden mutation. Journal of Pediatric Surgery 43 , e17-e19 /Sharathkumar AA,Stanley JC.Management of a child with renal artery stenosis and homozygous factor V Leiden mutation[J].2008,43(01)....