High-Grade GliomaHigh-grade gliomas are defined as tumors of glial origin with a very low incidence rate in infants and young children. They form part of the spectrum of primary intrinsic CNS and spinal cord tumors...doi:10.1007/978-3-319-55430-3_12Scheryll Alken...
Studies included adult patients (≥ 16 years old) receiving radiotherapy or chemoradiotherapy following a diagnosis of a high-grade glioma. Studies needed to specify the proportion of the sample that exhibited PsP, which was confirmed no more than 6 months following radiotherapy. Intervention Studies...
GC, gliomatosis cerebri; HGG, high-grade glioma; ped, pediatric Full size image Central radiological review The central radiological review was performed teleradiologically by two experienced neuroradiologists in consensus (VDR and BB). Preoperative magnetic resonance imaging (MRI) characterized the ...
Sanger sequencing of the smaller PCR products of one patient with glioma confirmed the deletion of exons 7 and 8 (not shown). Of note, due to the lack of high-quality genomic DNA from these clinical samples we could not discriminate in these samples whether METΔ7–8resulted from a mutatio...
Previous reports indicate HOXD9 may behave as an oncogene in glioma38 and breast cancer39. Consistent with this, in functional assays we showed that higher HOXD9 expression reduced apoptosis, increased proliferation under conditions of high cell density and enhances ectopic proliferation of cells in ...
High grade glioma radiation therapy on a high field 1.5 Tesla MR-Linac - workflow and initial experience with daily adapt-to-position (ATP) MR guidance: A first report 2022, Frontiers in Oncology Integrated MRI-guided radiotherapy — opportunities and challenges 2022, Nature Reviews Clinical Oncolog...
High-grade gliomaMalignant gliomaRadiotherapyRadiosurgeryBACKGROUND: The Manchester criteria for neurofibromatosis type 2 (NF2) include a range of tumors, and gliomas were incorporated in the original description. The gliomas are now widely accepted to be predominantly spinal cord ependymomas.King, Andrew...
Patients and methods: Two-hundred and eleven patients with primary high grade glioma were treated at the Royal Marsden NHS Trust between 1987 and 1997 with accelerated radiotherapy (55 Gy in 34 fractions twice daily), to planning target volume (PTV) defined as enhancing tumour and a 3 cm ...
A multicenter, two stage phase II study, investigated irinotecan plus temozolomide in children with newly diagnosed high grade glioma. The primary endpoint
HOXD9is a little-studied homeobox gene known to be involved in the development of gynecological organs36and mammary gland maturation during pregnancy and lactation37. Previous reports indicateHOXD9may behave as an oncogene in glioma38and breast cancer39. Consistent with this, in functional assays we...