The loss of two of the four genes is referred to asα-thalassemia trait.The pair of deleted genes may be from the same chromosome, or one α-globin gene may be deleted from each of the two chromosomes. The former situation is more common in Asian populations, whereas the latter is witne...
Patients with sickle cell trait may experience mild if any, symptoms at all. In sickle cell disease, symptoms are more significant, especially in episodes of acute crisis. These symptoms can include: Generalized body aches and pain Chest pain Bone pain Shortness of breath Ulceration of the ...
ROC analysis was performed to determine the predictive capacity of Ret-He levels in the diagnosis of IDA.Ninety-eight children with a mean age of 12.9±0.6 years were included. The Ret-He levels in the thalassemia trait group (26.7±2.4 pg), the ID group (29.0±2.9 pg), the IDA group...
17 The carrier state of sickle cell trait provides some protection against severe forms of malaria, believed to be the reason for the evolutionary persistence and high incidence of the mutant allele.18 There are believed to have been at least five separate spontaneous mutations of the allele ...
The mean corpuscular volume when determined by electronic counter is an accurate tool for identification of children with microcytosis due to either iron deficiency or thalassemia trait. The purpose of this report is to describe the norm... M.D. Marion A. Koerper a b,M.D. William C. Mentze...
Patients with sickle cell trait may experience mild if any, symptoms at all. In sickle cell disease, symptoms are more significant, especially in episodes of acute crisis. These symptoms can include: Generalized body aches and pain Chest pain Bone pain Shortness of breath Ulceration of the ...
trait give more Hb than other persons.Conclusion:Hb may have different existing state in RBC and thus it can be mostly released from RBC with first time of electrophoresis,with some residue in RBC released in the second time of electrophoresis.The blood sample of β-thalassemia trait disclosed ...
Hemoglobin A_1c: Teaching a New Dog Old Tricks In this issue, Ziemer and colleagues confirm that black persons tend to have higher HbA1c levels than white persons at any given mean glucose level. This editorial calls for research that explores the sources and effects of the observed ... HR...
Mean corpuscular volumeThalassemia traitGene sequencingBACKGROUND Iron deficiency anemia(IDA)and thalassemia trait(TT)are the most common microcytic and hypochromic anemias.Differentiation between mild TT and early IDA is still a clinical challenge.AIM To develop and validate a new index for ...
Hemoglobin (Hb)-SC disease results from a combination of sickle cell trait coinherited with the β-globin C trait. This results in a sickling condition with generally milder hemolytic anemia and less frequent acute and chronic complications. Sickle cell trait combined with a null β-globin ...