a severe hereditary form ofanemiain which the cells become crescent-shaped when oxygen is lacking. The abnormal sickle-shaped cells die prematurely and may become lodged in small blood vessels, potentially obstructing the microcirculation and leading to tissue damage. The sickling trait is found main...
N. M. Nseka心血管病(英文)Lepira FB, Mukendi TK, Mbutiwi FIN, Makulo JR, Sumaili EK, Kayembe PK, et al. Sickle cell trait, hemoglobin levels and anemia among black patients with predialysis chronic kidney disease: a post hoc analysis. World J Cardiovasc Dis. 2016;6:258....
Symptoms of sickle cell anemia vary depending on its severity. Patients with sickle cell trait may experience mild if any, symptoms at all. In sickle cell disease, symptoms are more significant, especially in episodes of acute crisis. These symptoms can include: Generalized body aches and pain ...
an abnormal Hb with substitution of lysyl residue for glutamyl at the 6th position of the β chain, of formula α22Aβ26Glu→Lys, this type reduces the normal plasticity of erythrocytes. Heterozygotes: Hb C trait, about 28-44% of total Hb is Hb C, no anemia. Homozygotes: nearly all ...
G., who clinically had sickle cell anemia. However, by starch block electrophoresis, two distinct major hemoglobins were demonstrable; they were subsequently identified as Hb S and GPhil./S. Thus, in the propositus, the hitherto undescribed coincidence of a homozygous β chain abnormality with ...
Blacks with sickle cell trait or hemoglobin C trait had 77% (95% CI = 22-155) and 42% (95% CI = 1-100) higher rates than whites and blacks with normal hemoglobin. Conclusion: Black children with sickle cell trait or hemoglobin C trait have an increased risk of invasive pneumococcal ...
Related to Hemoglobin, sickle: sickle cell trait, sickle cell anemia, sickle cell diseaseThesaurusAntonymsRelated WordsSynonymsLegend: Switch to new thesaurus Noun 1. sickle-cell disease - a congenital form of anemia occurring mostly in blacks; characterized by abnormal blood cells having a crescent...
Materials and Methods: Three groups were studied and consisted in 31 controls (group AA), 26 sickle cell trait (group AS) and 29 SCD patients (group SS) at steady state. Hemoglobin phenotype was assessed by combination of cation-exchange high performance chromatography (beta-thal short program ...
Define Hemoglobine. Hemoglobine synonyms, Hemoglobine pronunciation, Hemoglobine translation, English dictionary definition of Hemoglobine. n. The protein in the red blood cells of vertebrates that carries oxygen from the lungs to tissues and that consis
A hemoglobin test is often used to detect anemia, which is a deficiency of RBC that can have adverse health effects. While hemoglobin can be tested on its own, it’s more often tested as part of acomplete blood count(CBC) test that also measures levels of other types of blood cells. ...