The patient was an African American girl, originally diagnosed as homozygous Hb C during neonatal screening. When seen in our clinic, hematological data for both the child and her mother (Hb C trait) indicated mild anemia with slightly low mean corpuscular volume (MCV) but normal red blood ...
A heterozygote for Hb<inf>β</inf>S, Hb<inf>β</inf>C and Hb<inf>α</inf>G Philadelphia in a family presenting evidence for heterogeneity of hemoglobin alpha chain loci 1975, The American Journal of Medicine Show abstract Sickle cell anemia and central nervous system infarction: A neuropath...
镰状细胞特征(sickle cell trait,HbAS)的Hb分离得到60% 的HbA、40%的HbS、正常HbF和高达4.5%的HbA 2。用阳离子交换HPLC检测时,HbAS在HbA 1c低水平时会导致一定程度的虚假升高,但在HbA 1c水平升高时则无影响。硼酸盐亲和层析在这种情况下可得到准确的估计值。镰状细胞贫血(sickle cell anemia,HbSS)的Hb电泳得到...
(HbE) variant could have an artificially lower HbA1c relative to individuals without HbE,18 we conducted an additional analysis excluding participants from the South region (where the HbE trait is most common) to determine whether relationships among ID, anemia, IDA and diabetes classification by ...
Results for HbE trait samples were statistically significantly different from those of HbAA samples (P<0.01), but the differences were not clinically significant (mean bias -0.21% and -0.23% Hb [A.sub.1c] at 6% and 9% Hb A1c, respectively). [1] Nonstandard abbreviations: Hb A1c, hemoglo...
C Altay,WA Schroeder,THJ Huisman 摘要: A combination of 2 forms of thalassemia has been observed in a member of a South Carolina family. The proposita, a 34-year-old black female with hemolytic anemia, had over 50% fetal hemoglobin, an elevated level of hemoglobin A2, and in vitro ...
38. Roberts WL, McCraw M, Cook CB. Effects of sickle cell trait and hemoglobin C on determinations of HbA1c by immunoassay method. Diabetes Care 1998;21:983-6. 39. Roberts WL, Frank EL, Moulton L, Papadea C, Noffsinger J, Ou C. Effects of nine hemoglobin variants on five glycated...
The results demonstrate that the DNA-based methods, RED and ARMS, are efficient diagnostic tools in detecting HbCS in homozygotes and heterozygotes, whereas automated HPLC gave accurate results for homozygous HbCS, but misidentified (no peak) some cases of HbCS trait. Standard hematological ...
Velasco-Rodriguez D, Alonso-Dominguez JM, Gonzalez-Fernandez FA, Villarrubia J, Ropero P, Martinez-Nieto J, de la Fuente F, Guillen R, Acedo N, Seri C. Cava F. Deltabeta-thalassemia trait: how can we discriminate it from beta-thalassemia trait and iron deficiency anemia? Am J Clin Patho...
Usefulness of Cell Counter–Based Parameters and Formulas in Detection of β-Thalassemia Trait in Areas of High Prevalence High-performance liquid chromatographyHPLCCell counterIron deficiency anemiaHemoglobin A2The present study aimed to retrospectively evaluate the usefulness of cell ... DA Rathod,K ...