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The intrinsic GTPase activity is accelerated by GAP (GTPase activating protein). The transition from the active GTP bound to the inactive GDP bound form is accompanied by a conformational change which has been characterized by time-resolved x-ray structure analysis (2). In order to specify in ...
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The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests a role in the immune response to antigenic stimuli. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. 仅用于科研。不用于诊断过程。未经明确授权不得转售。 This...
别名: c-H-ras, CBAS/HAS, CHARAS1, cHras, CTLO, GTPase HRas, H-Ras-1, Ha-Ras, HAMSV, HaRas, HRAS, HRas1, HRASIDX, KRAS, N-terminally processed, NRAS, p21ras, RASH_HUMAN, RASH1, Transforming protein p21, vHaras Harvey rat sarcoma viral oncogene homolog 操作步骤:Ⅰ 实体组织蛋白的...
(i.e., the snatching of PM fragments at the IS10), previous studies of TNTs forming among Jurkat cells did not demonstrate seamless cell-to-cell transfer of PM-asso- ciated proteins.5 In this regard, in previous studies we have discovered that H-Ras – a small GTPase that undergoes ...
Hyperactive Ras signalling is found in most cancers. Ras proteins are only active in membrane nanoclusters, which are therefore potential drug targets. We previously showed that the nanocluster scaffold galectin-1 (Gal1) enhances H-Ras nanoclustering via
H10915 Human T-cell specific GTPase,Tgtp ELISA Kit ELISA. 96T/48T H10916 Human farnesyl-diphosphate farnesyltransferase 1,FDFT1 ELISA Kit ELISA. 96T/48T H10917 Human D-Lactate Dehydrogenase,D-LDH ELISA Kit ELISA. 96T/48T H10918 Human α1-Antitrypsin,α1-AT ELISA Kit ELISA. 96T/48T ...
RASAL2 (H-48): sc-68358RASAL2 (Ras protein activator like 2), also known as nGAP, is a Ras GTPase- activating protein. RAS proteins cycle between an active guanosine-triphos- phate (GTP) bound form and an inactive, guanosine-diphosphate (GDP) bound form. GTPase-activating proteins (GAPs...
c-kit is a type of tyrosine kinase receptor that is located in the membranes of ICCs and regulates several important proteins, such as phosphatidylino- VLWRO ·NLQDVH 3,NLQDVH SKRVSKROLSDVH &DŽ 3/&DŽ SKRV- pholipase D, SRC family kinases, p21ras GTPase-...