Graft-Versus-Host Disease (GvHD) is a condition that can occur after a stemcellor bone marrow transplant in which the newly transplanted donor cells attack the transplant recipient's body. This immune response can cause a variety of symptoms and complications, ranging from mild to sever...
That can be part of the armamentarium, but we want to minimize exposure to steroids if it’s needed. A steroid-free treatment for certain customized patients who we could identify is something that I hope we can achieve in the future. Corey Cutler, MD, MPH, FRCPC: Hannah, what are your...
“It can sometimes be difficult to distinguish between acute and chronic GVHD. It’s always a good idea to review symptoms with the bone marrow transplant team, because sometimes the signs and symptoms can be subtle,” saysShernan Holtan, MD, the chief of the bone marrow and transplantation ...
What Causes Graft Versus Host Disease? Graft versus host disease (GVHD) is a complication of cell transplantation caused by an immune-mediated response that results from an interaction between a donor’s and a recipient’s immunity. It occurs when the donor’s T-cells (the graft) see the ...
What to keep in mind Connect with others who’ve been there Find online groups, support meetings, one-on-one mentor services, and other opportunities to talk with people like you dealing with GVHD. Find support I’ve joined two Facebook groups that are really helpful. Sometimes I have a ...
What are risk factors for GVHD? Patients undergoing bone marrow transplant (stem cell transplant) from a donor are at increased risk for GVHD. Medical research has also shown that the likelihood of developing GVHD increases with certain underlying disease states. The disease is also more likely to...
Learn what acute GVHD is, when it usually happens, the signs and symptoms, and what occurs in your body.
Also, the transplant setting in China is a bit different from what it is [in the United States] and other parts of the world. Their most common donor source is haploidentical transplants, and it’s not based on a post-transplant cyclophosphamide platform. You wonder about GVHD and how ...
Although GVHD is a common cause of abdominal pain and diarrhea posttransplant, the differential is broad and infections are frequently the cause, either alone or in combination with GVHD. Several frequent, as well as infrequent, infections are presented, in common and uncommon presentations....
Hutt Department of Paediatric Haematology-Oncology and BMT, Edmond and Lily Safra Children Hospital, Sheba Medical Center, Tel-Hashomer, Israel e-mail: dhutt@sheba.health.gov.il 11.1 What Is GvHD? 11.1.1 Definitions Acute GvHD is a reaction of donor immune cells against host tissues. The...