Jakafi is used to treat adults and children 12 years of age and older with acute graft-versus-host disease (GVHD) who have taken corticosteroids and they did not work well enough. Jakafi is also used to treat adults and children 12 years of age and older with chronic GVHD who have taken...
The benefit of this effect must be balanced with the risk of lethal GVHD, and this balance comes in the way of donor selection and immune suppression. The role of the GVL effect is probably best evidenced by studies that show those patients who experience GVHD have a lower risk of relapse...