What Causes Graft Versus Host Disease? Graft versus host disease (GVHD) is a complication of cell transplantation caused by an immune-mediated response that results from an interaction between a donor’s and a recipient’s immunity. It occurs when the donor’s T-cells (the graft) see the ...
How chronic graft versus host disease (cGvHD) can accompany stem cell transplants, and what you need to know about treatment.
What is the Role of Biomarker Testing in GVHD? EP: 6.Overview of Therapy for Steroid-Refractory Acute Graft Versus Host Disease EP: 7.Steroid-Refractory GVHD: Enrolling Patients on Clinical Trials EP: 8.Identifying the Role of the Microbiome in HSCT and GVHD EP: 9.Improving the Early ...
stem cells and other cells of the immune system cannot be transfused into just anyone. For stem cell transfusions of any type, the body's immune system can mistakenly start attacking the patient's own body. This is known as graft-versus-host disease (GvHD) ...
These patients are on high dose prednisone for the chronic GVHD which they have but the steroid is not effective, or there is an attempt to reduce the dosage or eliminate prednisone completely. This phase 1 clinical trial is hoping to see is the effect can reduce/eliminate the prednisone ...
Due to the immunosuppressive effect of Tregs, their potential for preventing graft-versus-host disease (GVHD) after HSCT in MM has been extensively explored. Studies have shown that deficiency of Tregs after Allo-HSCT is associated with severe acute GVHD [153], proliferation of Tregs and activatio...
ECP has also been used in several other autoimmune diseases including acute GVHD, solid organ transplant rejection and Crohn's disease, with some success. ECP is a relatively safe procedure, and side-effects are typically mild and transient. Severe reactions including vasovagal syncope or infections...
Complications, including graft-versus-host disease (GVHD), in people who have received a bone marrow (stem cell) transplant that uses donor stem cells (allogeneic). These complications can be serious and can lead to death. These complications may happen if you underwent transplantation either befor...
ocular interventions or surgeries. Specific conditions that fall under this category include rheumatoid arthritis, Sjogren’s syndrome, thyroid eye disease, and dry eye induced by another autoimmune disease. Ocular surface disease can also be a result of chronic graft versus host disease (GVHD). ...
Complications, including graft-versus-host disease (GVHD), in people who have received a bone marrow (stem cell) transplant that uses donor stem cells (allogeneic). These complications can be serious and can lead to death. These complications may happen if you underwent transplantation either befor...